An analysis of S-RBD quantitative antibody levels in post-vaccination of health workers at Jemursari Islamic hospital and Menur Mental Hospital Surabaya

The COVID-19 disease caused by the SARS-CoV-2 virus has been a shared global challenge to date. COVID-19 vaccination is one of th solutions to build herd immunity. The level of neutralizing antibodies in the body after vaccination is essential to investigate. This research aimed to analyze the post-vaccination of S-RBD quantitative antibody levels of health workers at Jemursari Islamic Hospital and Menur Mental Hospital Surabaya. The research design employed was the descriptive study involving 43 samples determined by a simple random sampling technique. The independent variable was the quantitative antibody level of S-RBD. The primary research data was collected from diagnostic laboratory results of health workers’ blood samples and then analyzed for quantitative antibody levels using Mindray CL-900i. This research showed that of the 43 samples analyzed, 100% showed reactive results (>1000 U/mL) or positive quantitative antibodies to S-RBD after vaccination. In conclusion, there were significant levels of quantitative SARS-CoV-2 antibodies in the blood of health workers after the third dose of COVID-19 vaccination.