Formation of new substituted (1,3)oxazepine 1,5-diones via reaction of Exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic Anhydride with Schiff’s bases

1,3-oxazepine-1,5-diones, and its derivatives are quite substantial compounds utilized in various field like biological activity. Therefore several compounds have been prepared by abundant methods. This sitting work comprises the preparation of heterocyclic seven-membered ring compounds obtained from Schiff's bases.Benzidine and benzene-1,3-diamine were condensed by refluxing with various aromatic aldehydes with few drops of glacial acetic acid as catalyst in absolute ethanol to produce Schiff bases. These Schiff's bases were treated in anhydrous 1,4-dioxane with Exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic Anhydride under reflux in circumstances that gave substituted 1,3-oxazepine-1,5-dione. The products were isolated, purified and characterized by their melting points , FT-IR and 1HNMR spectra, which are found to be 1,3oxazepine 1,5-diones derivatives.