Effect of nanoparticles dewandaru fruits extract to reduce total cholesterol on hyperlipidemic mice

Dewandaru (Eugenia uniflora L.) is a plant that contains flavonoids, tannins, terpenoids, and essential oils and used as traditional medicine. This study aimed to determine the activity of 70% ethanol extract of dewandaru fruit and nanoparticle form of dewandaru fruit extract (NP) to reduce total ch...

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Hauptverfasser: Lamdho, Onisa Triwal Wafa, Angelina, Marissa, Dewijanti, Indah D., Dewi, Rizna Triana
Format: Tagungsbericht
Sprache:eng
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Zusammenfassung:Dewandaru (Eugenia uniflora L.) is a plant that contains flavonoids, tannins, terpenoids, and essential oils and used as traditional medicine. This study aimed to determine the activity of 70% ethanol extract of dewandaru fruit and nanoparticle form of dewandaru fruit extract (NP) to reduce total cholesterol levels in hyperlipidemic mice. DDY mice were divided into 8 treatment groups, each consisting of 4 mice: group I (Normal); group II (negative control); group III (positive control); group IV (dose 100 mg/kg bw); group V (dose 200 mg/kg bw); group VI (dose 400 mg/kg bw); group VII (NP dose 200 mg/kg bw) and group VIII (NP dose 400 mg/kg bw). Data of reducing cholesterol potential were analyzed using One way-Anova with the significant difference limit between the treatment group, and negative control is P
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0110178