Biosynthesis of cadmium oxide nanoparticles (CdO NPS) using aqueous rhizome extract of curcuma for biological applications

This research covers the bio preparation of cadmium oxide nanoparticles (CdO NPS) with the use of aqueous plant extracts from the Curcuma rhizome. Characterization of CdO NPs was performed using (XRD), UV–VIS spectroscopy, (FT-IR), (AFM), and (FE-SEM). The XRD technique has confirmed the crystallinity of CdO NPs with an average crystalline CdO NPs scale of 33,21nm. The optical bandgap of CdO NPs is 5.5 eV. The nanoparticle size of the particles is 571.32 nm as seen (FE-SEM) and the average diameter of CdO NPs is 70.41 nm as shown by AFM. CdO NPs is screened for antimicrobial activity against a variety of human pathogens, including Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Escherichia coli, Candida albicans, and Trichophyton rubrum using agar well diffusion. The anticancer efficacy of CdO NPs against human colon cells (HT-29) was tested using an MTT assay. The results showed that CdO nanoparticles demonstrated superior antibacterial activity in the area of antimicrobial strain inhibition. CdO NPs have shown substantial anticancer.