Estimation the levels of spermidine and spermine in sera of inflammatory bowel disease patients

This study was aimed estimate the levels of spermidine (SPD), spermine (SPM) and total peroxidase activity in serum of Iraqi patients with inflammatory bowel disease (IBD). A total 60 IBD patients were enrolled in the present research the age range is 16-40 years. They were classified into two main groups: 30 patients (15male & 15female) with Crohn’s disease (CD), and 30 patients (15male & 15female) with ulcerative colitis (UC). The healthy control group (HC) consist of 30 healthy subjects (15 male & 15 females). SPD and SPM were measured by using HPLC technique. The levels of serum of SPD were (90.22±20.05 and 141.88±24.16 µg/ml) in the CD and UC patients, respectively. These values refer to a highly significant increase (p