Immunological and physiological study of itching caused by Sarcoptes scabiei before and after treatment
The present study conducted on thirty male patients who were infected with scabies. Blood samples collected before and after treatment in addition to 30 male controls, were used in immunological study to determine the effect of infection with scabies on concentrations of Tropomyosin, Paramyosin, Mel...
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| description | The present study conducted on thirty male patients who were infected with scabies. Blood samples collected before and after treatment in addition to 30 male controls, were used in immunological study to determine the effect of infection with scabies on concentrations of Tropomyosin, Paramyosin, Melatonin, and Cathepsin-D before and after treatment. All these cases were collected from Healthy centers of camps Kaparto1and 2, Sharyia and Khanki in Duhok governorate and diagnosed by light microscopic method for examining the Sarcoptes scabiei mite or its eggs, at laboratories of these centers from March 2019 to about 30 January 2020. The results of study revealed the levels of Tropomyosin, Paramyosin, Cathepsin-D were significantly increasing (P |
| doi_str_mv | 10.1063/5.0027515 |
| format | Conference Proceeding |
| fullrecord | <record><control><sourceid>proquest_scita</sourceid><recordid>TN_cdi_scitation_primary_10_1063_5_0027515</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2467234876</sourcerecordid><originalsourceid>FETCH-LOGICAL-p288t-fe418e70e8c83127e511f5143db3822217b596379f506f770ebbbd860b0ded3a3</originalsourceid><addsrcrecordid>eNp90EtLxDAUBeAgCo6jC_9BwJ3QMY_m0aUMPgYGXKjgLiRtMpNh2tQkFfrvrTroztWFy8c5cAC4xGiBEac3bIEQEQyzIzDDjOFCcMyPwQyhqixISd9OwVlKuwlVQsgZ2KzadujCPmx8rfdQdw3st2Pyv5-Uh2aEwUGf663vNrDWQ7INNCN81rEOfbYJplobbz001oVov1O0yzbCHK3Ore3yOThxep_sxeHOwev93cvysVg_PayWt-uiJ1LmwtkSSyuQlbWkmAjLMHYMl7QxVBJCsDCs4lRUjiHuxASNMY3kyKDGNlTTObj6ye1jeB9symoXhthNlYqUXBBaSsEndf2jUu2zzj50qo--1XFUGKmvIRVThyH_wx8h_kHVN45-AjMydMM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype><pqid>2467234876</pqid></control><display><type>conference_proceeding</type><title>Immunological and physiological study of itching caused by Sarcoptes scabiei before and after treatment</title><source>AIP Journals Complete</source><creator>Saleh, Jasim M. ; Al-Hadraawy, Saleem Khteer ; AL-Dhalimi, Muhsin A.</creator><contributor>Hashim, Jasim Hanoon ; Aaber, Zeyad S ; Abdulateff, Ahmed Mahmood ; Madlool, Thaer Mahdi ; Nasir, Ibtisam Abbas ; Joda, Baker A ; Mohammed, Adnan Ibrahim</contributor><creatorcontrib>Saleh, Jasim M. ; Al-Hadraawy, Saleem Khteer ; AL-Dhalimi, Muhsin A. ; Hashim, Jasim Hanoon ; Aaber, Zeyad S ; Abdulateff, Ahmed Mahmood ; Madlool, Thaer Mahdi ; Nasir, Ibtisam Abbas ; Joda, Baker A ; Mohammed, Adnan Ibrahim</creatorcontrib><description>The present study conducted on thirty male patients who were infected with scabies. Blood samples collected before and after treatment in addition to 30 male controls, were used in immunological study to determine the effect of infection with scabies on concentrations of Tropomyosin, Paramyosin, Melatonin, and Cathepsin-D before and after treatment. All these cases were collected from Healthy centers of camps Kaparto1and 2, Sharyia and Khanki in Duhok governorate and diagnosed by light microscopic method for examining the Sarcoptes scabiei mite or its eggs, at laboratories of these centers from March 2019 to about 30 January 2020. The results of study revealed the levels of Tropomyosin, Paramyosin, Cathepsin-D were significantly increasing (P <0.05) in their concentrations before treatment in patients with scabies (2. 6136 ±0. 21372 pg /ml), (29. 234 ±1. 8010 pg /ml). (53. 248 ±3. 7237 pg /ml) respectively, in compared to the control group (1. 3012±0. 15098 pg /ml), (20. 493±3. 2801 pg /ml), (30. 675±2. 5568 pg /ml) respectively, but after treatment the results of study revealed that Cathepsin-D in patients with scabies non- significantly increased (P< 0.05) 11.254 ±1.0982 pg /ml) in compared to the control group (10. 970±1. 0610 pg /ml). Also the serum levels of Tropomyosin after treatment was significantly decreased (P< 0.05) (16.121 ±2.1374 pg /ml) in compared to the control group (20. 493±3. 2801 pg /ml), while paramyosin after treatment was non-significantly decrease (P< 0.05) (28.631 ±2.4671 pg /ml) in compared to the control group (20. 493±3. 2801 pg /ml). Also the present study revealed that serum levels of Melatonin in male patients infected with S. scabiei before and after treatment were non-significant decrease (P< 0.05) (7. 8424 ± 0. 79423 pg /ml), (9.3013 ±1.2114 pg /ml), respectively in compared to the control group (10. 185±1. 3965 pg /ml). From the current study we conclude that the scabies disease influences on the human immunity represented by the Tropomyosin, Paramyosin, Melatonin and Cathepsin-D in patients infected with scabies and may be used as good biomarkers in detection of scabies. We believe that melatonin is a good diagnostic biochemical marker as its associated with itching.</description><identifier>ISSN: 0094-243X</identifier><identifier>EISSN: 1551-7616</identifier><identifier>DOI: 10.1063/5.0027515</identifier><identifier>CODEN: APCPCS</identifier><language>eng</language><publisher>Melville: American Institute of Physics</publisher><subject>Biomarkers ; Diagnostic systems ; Eggs ; Immunology ; Itching ; Melatonin</subject><ispartof>AIP conference proceedings, 2020, Vol.2290 (1)</ispartof><rights>Author(s)</rights><rights>2020 Author(s). Published by AIP Publishing.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://pubs.aip.org/acp/article-lookup/doi/10.1063/5.0027515$$EHTML$$P50$$Gscitation$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,790,4498,23909,23910,25118,27901,27902,76126</link.rule.ids></links><search><contributor>Hashim, Jasim Hanoon</contributor><contributor>Aaber, Zeyad S</contributor><contributor>Abdulateff, Ahmed Mahmood</contributor><contributor>Madlool, Thaer Mahdi</contributor><contributor>Nasir, Ibtisam Abbas</contributor><contributor>Joda, Baker A</contributor><contributor>Mohammed, Adnan Ibrahim</contributor><creatorcontrib>Saleh, Jasim M.</creatorcontrib><creatorcontrib>Al-Hadraawy, Saleem Khteer</creatorcontrib><creatorcontrib>AL-Dhalimi, Muhsin A.</creatorcontrib><title>Immunological and physiological study of itching caused by Sarcoptes scabiei before and after treatment</title><title>AIP conference proceedings</title><description>The present study conducted on thirty male patients who were infected with scabies. Blood samples collected before and after treatment in addition to 30 male controls, were used in immunological study to determine the effect of infection with scabies on concentrations of Tropomyosin, Paramyosin, Melatonin, and Cathepsin-D before and after treatment. All these cases were collected from Healthy centers of camps Kaparto1and 2, Sharyia and Khanki in Duhok governorate and diagnosed by light microscopic method for examining the Sarcoptes scabiei mite or its eggs, at laboratories of these centers from March 2019 to about 30 January 2020. The results of study revealed the levels of Tropomyosin, Paramyosin, Cathepsin-D were significantly increasing (P <0.05) in their concentrations before treatment in patients with scabies (2. 6136 ±0. 21372 pg /ml), (29. 234 ±1. 8010 pg /ml). (53. 248 ±3. 7237 pg /ml) respectively, in compared to the control group (1. 3012±0. 15098 pg /ml), (20. 493±3. 2801 pg /ml), (30. 675±2. 5568 pg /ml) respectively, but after treatment the results of study revealed that Cathepsin-D in patients with scabies non- significantly increased (P< 0.05) 11.254 ±1.0982 pg /ml) in compared to the control group (10. 970±1. 0610 pg /ml). Also the serum levels of Tropomyosin after treatment was significantly decreased (P< 0.05) (16.121 ±2.1374 pg /ml) in compared to the control group (20. 493±3. 2801 pg /ml), while paramyosin after treatment was non-significantly decrease (P< 0.05) (28.631 ±2.4671 pg /ml) in compared to the control group (20. 493±3. 2801 pg /ml). Also the present study revealed that serum levels of Melatonin in male patients infected with S. scabiei before and after treatment were non-significant decrease (P< 0.05) (7. 8424 ± 0. 79423 pg /ml), (9.3013 ±1.2114 pg /ml), respectively in compared to the control group (10. 185±1. 3965 pg /ml). From the current study we conclude that the scabies disease influences on the human immunity represented by the Tropomyosin, Paramyosin, Melatonin and Cathepsin-D in patients infected with scabies and may be used as good biomarkers in detection of scabies. We believe that melatonin is a good diagnostic biochemical marker as its associated with itching.</description><subject>Biomarkers</subject><subject>Diagnostic systems</subject><subject>Eggs</subject><subject>Immunology</subject><subject>Itching</subject><subject>Melatonin</subject><issn>0094-243X</issn><issn>1551-7616</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2020</creationdate><recordtype>conference_proceeding</recordtype><recordid>eNp90EtLxDAUBeAgCo6jC_9BwJ3QMY_m0aUMPgYGXKjgLiRtMpNh2tQkFfrvrTroztWFy8c5cAC4xGiBEac3bIEQEQyzIzDDjOFCcMyPwQyhqixISd9OwVlKuwlVQsgZ2KzadujCPmx8rfdQdw3st2Pyv5-Uh2aEwUGf663vNrDWQ7INNCN81rEOfbYJplobbz001oVov1O0yzbCHK3Ore3yOThxep_sxeHOwev93cvysVg_PayWt-uiJ1LmwtkSSyuQlbWkmAjLMHYMl7QxVBJCsDCs4lRUjiHuxASNMY3kyKDGNlTTObj6ye1jeB9symoXhthNlYqUXBBaSsEndf2jUu2zzj50qo--1XFUGKmvIRVThyH_wx8h_kHVN45-AjMydMM</recordid><startdate>20201204</startdate><enddate>20201204</enddate><creator>Saleh, Jasim M.</creator><creator>Al-Hadraawy, Saleem Khteer</creator><creator>AL-Dhalimi, Muhsin A.</creator><general>American Institute of Physics</general><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>20201204</creationdate><title>Immunological and physiological study of itching caused by Sarcoptes scabiei before and after treatment</title><author>Saleh, Jasim M. ; Al-Hadraawy, Saleem Khteer ; AL-Dhalimi, Muhsin A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p288t-fe418e70e8c83127e511f5143db3822217b596379f506f770ebbbd860b0ded3a3</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Biomarkers</topic><topic>Diagnostic systems</topic><topic>Eggs</topic><topic>Immunology</topic><topic>Itching</topic><topic>Melatonin</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saleh, Jasim M.</creatorcontrib><creatorcontrib>Al-Hadraawy, Saleem Khteer</creatorcontrib><creatorcontrib>AL-Dhalimi, Muhsin A.</creatorcontrib><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saleh, Jasim M.</au><au>Al-Hadraawy, Saleem Khteer</au><au>AL-Dhalimi, Muhsin A.</au><au>Hashim, Jasim Hanoon</au><au>Aaber, Zeyad S</au><au>Abdulateff, Ahmed Mahmood</au><au>Madlool, Thaer Mahdi</au><au>Nasir, Ibtisam Abbas</au><au>Joda, Baker A</au><au>Mohammed, Adnan Ibrahim</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Immunological and physiological study of itching caused by Sarcoptes scabiei before and after treatment</atitle><btitle>AIP conference proceedings</btitle><date>2020-12-04</date><risdate>2020</risdate><volume>2290</volume><issue>1</issue><issn>0094-243X</issn><eissn>1551-7616</eissn><coden>APCPCS</coden><abstract>The present study conducted on thirty male patients who were infected with scabies. Blood samples collected before and after treatment in addition to 30 male controls, were used in immunological study to determine the effect of infection with scabies on concentrations of Tropomyosin, Paramyosin, Melatonin, and Cathepsin-D before and after treatment. All these cases were collected from Healthy centers of camps Kaparto1and 2, Sharyia and Khanki in Duhok governorate and diagnosed by light microscopic method for examining the Sarcoptes scabiei mite or its eggs, at laboratories of these centers from March 2019 to about 30 January 2020. The results of study revealed the levels of Tropomyosin, Paramyosin, Cathepsin-D were significantly increasing (P <0.05) in their concentrations before treatment in patients with scabies (2. 6136 ±0. 21372 pg /ml), (29. 234 ±1. 8010 pg /ml). (53. 248 ±3. 7237 pg /ml) respectively, in compared to the control group (1. 3012±0. 15098 pg /ml), (20. 493±3. 2801 pg /ml), (30. 675±2. 5568 pg /ml) respectively, but after treatment the results of study revealed that Cathepsin-D in patients with scabies non- significantly increased (P< 0.05) 11.254 ±1.0982 pg /ml) in compared to the control group (10. 970±1. 0610 pg /ml). Also the serum levels of Tropomyosin after treatment was significantly decreased (P< 0.05) (16.121 ±2.1374 pg /ml) in compared to the control group (20. 493±3. 2801 pg /ml), while paramyosin after treatment was non-significantly decrease (P< 0.05) (28.631 ±2.4671 pg /ml) in compared to the control group (20. 493±3. 2801 pg /ml). Also the present study revealed that serum levels of Melatonin in male patients infected with S. scabiei before and after treatment were non-significant decrease (P< 0.05) (7. 8424 ± 0. 79423 pg /ml), (9.3013 ±1.2114 pg /ml), respectively in compared to the control group (10. 185±1. 3965 pg /ml). From the current study we conclude that the scabies disease influences on the human immunity represented by the Tropomyosin, Paramyosin, Melatonin and Cathepsin-D in patients infected with scabies and may be used as good biomarkers in detection of scabies. We believe that melatonin is a good diagnostic biochemical marker as its associated with itching.</abstract><cop>Melville</cop><pub>American Institute of Physics</pub><doi>10.1063/5.0027515</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Biomarkers Diagnostic systems Eggs Immunology Itching Melatonin |
| title | Immunological and physiological study of itching caused by Sarcoptes scabiei before and after treatment |
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