Numerical approach of biological tissues/thin layer sensor interface behavior quantification

In this paper, we investigate the behavior of biological tissues coupled to a substrate (sensor) based on a numerical model taking into account the relationship between strain/stress components at the interface. Based on this study, the most appropriate biomechanical factors are understood and quantified in order to optimize the sensor/biological tissue interface conditions. A micromechanical description based on a mathematical formulation has been developed to evaluate the biomechanical behavior provided by a 20 viscoelastic model of Kelvin-Voigt. Based on the results, it appears that the model can be used effectively to characterize in-vivo the dynamic properties of soft tissues in order to adapt the biophysical properties of flexible sensors dedicated to optimal adhesion.