Immune response elicited by the oral administration of an intermediate strain of IBDV in chickens

The immune response elicited by the oral inoculation of an intermediate strain of infectious bursal disease virus was studied in chickens. A strong over expression of IL-6, IL-8, IFNα and IFNγ was observed in bursa at 3 days post inoculation together with an increase in splenic NO2 release. An influ...

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Veröffentlicht in:	Brazilian journal of microbiology 2014, Vol.45 (4), p.1521-1525
Hauptverfasser:	Carballeda, Juan Manuel, Zoth, Silvina Chimeno, Gómez, Evangelina, Lucero, María Soledad, Gravisaco, María José, Berinstein, Analía
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animal diseases Animals Birnaviridae Infections - immunology Birnaviridae Infections - veterinary Bursa of Fabricius - pathology Chickens Cytokines Cytokines - analysis Cytokines - genetics Flow cytometry Gene Expression Profiling Immunization Infectious bursal disease virus - immunology MICROBIOLOGY Nitric Oxide - analysis Polymerase chain reaction Poultry Poultry Diseases - immunology Spleen - pathology T-Lymphocytes - immunology Veterinary Microbiology
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Zusammenfassung:	The immune response elicited by the oral inoculation of an intermediate strain of infectious bursal disease virus was studied in chickens. A strong over expression of IL-6, IL-8, IFNα and IFNγ was observed in bursa at 3 days post inoculation together with an increase in splenic NO2 release. An influx of T-lymphocytes was also detected.
ISSN:	1517-8382 1678-4405 1678-4405
DOI:	10.1590/S1517-83822014000400049