Effects of Quercetin-Supplementation in NADH-Diaphorase Positive Neurons Subpopulations in the Ileum of Rats with Experimental Diabetes Mellitus

The effects of quercetin supplementation in NADH-diaphorase positive (NADH-d) neurons of streptozotocin-induced diabetic rats was carried in this study. Fifteen male rats were divided into three groups: normoglycemic (N), diabetic (D) and diabetic supplemented with quercetin (DQ). Whole mount prepar...

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Veröffentlicht in:International journal of morphology 2017-03, Vol.35 (1), p.236-241
Hauptverfasser: Pereira Alves, Angela Maria, de Paula, Anderson Luiz, Moreira, Cassio Rafael, Ferrari, Fernanda, Coelho Leal, Jean Paulo, Hatoum, Ualid Saleh, Vieira Silva, Helaine Maruska, Belato Alves, Eder Paulo, de Miranda Neto, Marcilio Hubner, Galvanini, Paulo Alexandre
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Sprache:eng
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Zusammenfassung:The effects of quercetin supplementation in NADH-diaphorase positive (NADH-d) neurons of streptozotocin-induced diabetic rats was carried in this study. Fifteen male rats were divided into three groups: normoglycemic (N), diabetic (D) and diabetic supplemented with quercetin (DQ). Whole mount preparations of the muscular layer of the ileum underwent NADH-d histochemistry for evidencing the NADH-d neuronal subpopulation. Quantitative analyzes were performed on 30 random fields, and morphometric analyzes in 100 neuronal bodies and nuclei per animal. The supplementation promoted a 44 % reduction in the neuronal density in D group when compared to N group (p
ISSN:0717-9502
0717-9502
DOI:10.4067/S0717-95022017000100039