The utility of urine sulphosalicylic acid testing in the detection of non-albumin proteinuria

We report two cases of immunoglobulin light chain proteinuria (Bence Jones proteinuria) detected by simple side-room invest-igations: urine dipstick negative/1+, but with strong positive pre-cipitation on addition of an equal volume of sulphosalicylic acid (SSA) 3%. We highlight a significant limita...

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Veröffentlicht in:	SAMJ: South African Medical Journal 2015-02, Vol.105 (2), p.153-153
Hauptverfasser:	Ndamase, S, Freercks, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumins Analysis Benzenesulfonates - urine Biomarkers - urine Care and treatment Case studies Diagnosis Diagnosis, Differential Female Health Care Sciences & Services Health Policy & Services Humans Male Medical Ethics Medicine, General & Internal Medicine, Legal Medicine, Research & Experimental Methods Middle Aged Properties Proteinuria Proteinuria - diagnosis Proteinuria - urine Salicylates - urine Salicylic acid Urinalysis - methods Urine
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Beschreibung
Zusammenfassung:	We report two cases of immunoglobulin light chain proteinuria (Bence Jones proteinuria) detected by simple side-room invest-igations: urine dipstick negative/1+, but with strong positive pre-cipitation on addition of an equal volume of sulphosalicylic acid (SSA) 3%. We highlight a significant limitation of urine dipstick testing, namely specificity for albumin, and the utility of SSA testing for the detection of urinary free light chain immunoglobulins.
ISSN:	0256-9574 2078-5135 2078-5135
DOI:	10.7196/samj.9270