3 cases of cocaine - levamisole syndrome in Medellín

Levamisole, an anthelmintic veterinary product is known to be used as an additive to cocaine that enhances the psychotropic effects of this substance. This mixture leads to reactions such as agranulocytosis, skin vasculitis and modulation of the immune system. Only the proper recognition, treatment of this entity and discontinuation of this substance consumption, leads to the disappearance of lesions; strongly suggesting the diagnosis. We present three cases of cocaine/levamisole syndrome in the city of Medellin and a review of the literature with some concepts related to this pathology.