SYNTHESIS AND ANTIOXIDANT ACTIVITY OF TWO ISOESPINTANOL DERIVATIVES

SYNTHESIS AND ANTIOXIDANT ACTIVITY OF TWO ISOESPINTANOL DERIVATIVES

The antioxidant activity of isoespintanol (1) hemisynthetic analogues, 4-bromo-2-isopropyl-3,6-dimethoxy-5-methylphe-nol (2) and 3-isopropyl-6-methylbenzene-1,2,4-triol (3), was evaluated using ABTS, DPPH and FRAP assays. Partial rationalization of the results is provided in terms of quantum chemica...

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Veröffentlicht in:Revista colombiana de química 2010-08, Vol.39 (2), p.173-180
Hauptverfasser: Galeano, Paula L., Gil, Maritza A., Gil, Jesús H., Otálvaro, León F., Saéz, Jairo A., Rojano, Benjamín A
Format: Artikel
Sprache:eng ; por
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CHEMISTRY, MULTIDISCIPLINARY
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Zusammenfassung:The antioxidant activity of isoespintanol (1) hemisynthetic analogues, 4-bromo-2-isopropyl-3,6-dimethoxy-5-methylphe-nol (2) and 3-isopropyl-6-methylbenzene-1,2,4-triol (3), was evaluated using ABTS, DPPH and FRAP assays. Partial rationalization of the results is provided in terms of quantum chemical calculations of bond dissociation enthalpy (BDE) and ionization potential (IP).
ISSN:0120-2804