Ischemic stroke progress evaluation by 31P NMR-based metabonomic of human serum

Ischemic stroke progress evaluation by 31P NMR-based metabonomic of human serum

In this work, chemometric analyses over 31P{¹H} NMR (nuclear magnetic ressonance) spectra of human blood serum permitted to discriminated ischemic stroke patients from health individuals due to changes in the chemical composition of phosphorus-containing compounds. These results indicate that 31P NM...

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Veröffentlicht in:Journal of the Brazilian Chemical Society 2014-06, Vol.25 (6), p.1143-1149
Hauptverfasser: Grandizoli, Caroline W. P. S., Lange, Marcos C., Novak, Felipe T. M., Campos, Francinete R., Barison, Andersson
Format: Artikel
Sprache:eng ; por
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CHEMISTRY, MULTIDISCIPLINARY
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Zusammenfassung:In this work, chemometric analyses over 31P{¹H} NMR (nuclear magnetic ressonance) spectra of human blood serum permitted to discriminated ischemic stroke patients from health individuals due to changes in the chemical composition of phosphorus-containing compounds. These results indicate that 31P NMR-based metabonomic allowed insights over the mechanism triggered by ischemic stroke.
ISSN:1678-4790
DOI:10.5935/0103-5053.20140084