Diterpene and other constituents from Stemodia maritima (Scrophulariaceae)

A new diterpene, (5S*,8S*,9R*,10S*)-11β,12β-epoxy-9α-hydroxy-19(4→3) abeo-abieta-3,13-diene-19,18-olide, together with the known compounds stemodin, D-mannitol, betulinic acid, a mixture of 3β-O-β-D-glucopyranosyl-β-sitosterol and 3β-O-β-D-glucopyranosylstigmasterol and 5,7,4'-trihydroxy-3,8,3&...

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Veröffentlicht in:Journal of the Brazilian Chemical Society 2010, Vol.21 (8), p.1581-1586
Hauptverfasser: Rodrigues, Francisco E. A., Lima, Jefferson Q., Oliveira, Maria da Conceição F. de, Vasconcelos, Jackson N., Santiago, Gilvandete M. P., Mafezoli, Jair, Braz-Filho, Raimundo, Arriaga, Angela M. C.
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Sprache:eng
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Zusammenfassung:A new diterpene, (5S*,8S*,9R*,10S*)-11β,12β-epoxy-9α-hydroxy-19(4→3) abeo-abieta-3,13-diene-19,18-olide, together with the known compounds stemodin, D-mannitol, betulinic acid, a mixture of 3β-O-β-D-glucopyranosyl-β-sitosterol and 3β-O-β-D-glucopyranosylstigmasterol and 5,7,4'-trihydroxy-3,8,3'-trimethoxyflavone were isolated from the leaves and stems of Stemodia maritima. Structural elucidation of all compounds was based on interpretation of spectral data, mainly NMR (1D and 2D) and MS, including comparison with values described in the literature.
ISSN:0103-5053
1678-4790
DOI:10.1590/S0103-50532010000800025