Therapeutic dose of Ginkgo biloba extract 761 may alter the urine excretion of Wistar rats

Therapeutic dose of Ginkgo biloba extract 761 may alter the urine excretion of Wistar rats

Wistar rats (n=20) were divided in two groups: G1 received 2 mg/kg of GBE (Ginkgo biloba extract 761), whereas G2 received the same volume of a sodium chloride solution (0.9%), both for 10 days. After a 7-day interval, the treatment was repeated for 8 days. Urine volume and food and water intake wer...

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Veröffentlicht in:Revista brasileira de farmacognosia 2012-10, Vol.22 (5), p.1060-1069
Hauptverfasser: Dalmacio, Monica S. C., Campos, Sylvia M. N., Carvalho, Jorge J. J., Pereira, Mário J. S., Nascimento, Ana Lúcia, Paschoal, Patricia O., Sobrinho, Andrea P., Pedruzzi, Monique M. B., Garrido, Valeria, Moreno, Silvana R. F., Teixeira, Gerlinde A. P. B., Cardoso, Gilberto P.
Format: Artikel
Sprache:eng
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PHARMACOLOGY & PHARMACY
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Zusammenfassung:Wistar rats (n=20) were divided in two groups: G1 received 2 mg/kg of GBE (Ginkgo biloba extract 761), whereas G2 received the same volume of a sodium chloride solution (0.9%), both for 10 days. After a 7-day interval, the treatment was repeated for 8 days. Urine volume and food and water intake were measured daily during this protocol. Histological assessments were performed. No significant difference (p>0.05) was observed in food and water intake of animals during treatment with GBE. Animals who received GBE had a smaller urine volume and increase of weight with a significance difference (p
ISSN:0102-695X
1981-528X
DOI:10.1590/S0102-695X2012005000093