Treatment topical with silver nanoparticles and Stryphnodendron Adstringens (Mart.) Coville in cervical lesions: randomized clinical trial

To assess the feasibility of incorporating technology as a new alternative for treating topics on cervical lesions. This is a randomized, double-blind, controlled clinical trial with a prospective design. During the realization of this study, 43 women were included and divided between groups A (oint...

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Veröffentlicht in:Revista da Escola de Enfermagem da U S P 2023-01, Vol.57, p.e20220338-e20220338
Hauptverfasser: Nascimento, Cristiane Araújo, Santos, Ana Caroline Melo Dos, Silva, Denise Macedo da, Barbosa, Nirliane Ribeiro, Moura, Edilson Leite de, Silva, Veracilda Bezerra da, Balliano, Tatiane Luciano, Figueiredo, Elaine Virginia Martins de Souza, Farias, Karol Fireman de, Pitta, Guilherme Benjamin Brandão
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Sprache:eng
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Zusammenfassung:To assess the feasibility of incorporating technology as a new alternative for treating topics on cervical lesions. This is a randomized, double-blind, controlled clinical trial with a prospective design. During the realization of this study, 43 women were included and divided between groups A (ointment without silver nanoparticles n = 23) and B (ointment with silver nanoparticles n = 20) clinically healthy and who used the unified health system. There were no significant differences when comparing before and after the use of ointment for IVA test (p = 0.15), Schiller test (p = 0.15), cellular changes (p = 0.47) and microbiological analysis (p = 0.89) through cytology. After use, no adverse reaction was observed in the sample studied. Based on the results identified in this study, identified that the product is safe and does not promote adverse events. Regarding the effectiveness of the product in uterine cervical lesions, it is necessary to continue the study in phase II. Registro de Ensaios Clínicos Brasileiros: UTN: U1111-1218-2820.
ISSN:0080-6234
1980-220X
1980-220X
DOI:10.1590/1980-220X-REEUSP-2022-0338EN