Development of Sarcomas in Marsh-Albino Mice Following Injection of Desoxycorticosterone Acetate in Sesame Oil.

Development of Sarcomas in Marsh-Albino Mice Following Injection of Desoxycorticosterone Acetate in Sesame Oil.

Summary Twenty-four mice of the Marsh-Albino strain were injected daily for a period of 3 months with desoxycorticosterone acetate (0.2 mg/0.1 cc) in sesame oil. Of these, 1 was killed 3 months after termination of treatment but showed no evidence of tumor, while 9 others, killed 6 months after term...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1953-05, Vol.83 (1), p.14-17
Hauptverfasser: Mirand, E. A., Reinhard, M. C., Goltz, H. L.
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creator Mirand, E. A.
Reinhard, M. C.
Goltz, H. L.
description Summary Twenty-four mice of the Marsh-Albino strain were injected daily for a period of 3 months with desoxycorticosterone acetate (0.2 mg/0.1 cc) in sesame oil. Of these, 1 was killed 3 months after termination of treatment but showed no evidence of tumor, while 9 others, killed 6 months after termination of treatments had subcutaneous tumors of two histological types, fibrosarcoma and myosarcoma. The remaining 10 mice are still alive; all show gross evidence of tumor formation, which became evident 6 months after completion of treatment.
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title Development of Sarcomas in Marsh-Albino Mice Following Injection of Desoxycorticosterone Acetate in Sesame Oil.
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