Development of Sarcomas in Marsh-Albino Mice Following Injection of Desoxycorticosterone Acetate in Sesame Oil.
Summary Twenty-four mice of the Marsh-Albino strain were injected daily for a period of 3 months with desoxycorticosterone acetate (0.2 mg/0.1 cc) in sesame oil. Of these, 1 was killed 3 months after termination of treatment but showed no evidence of tumor, while 9 others, killed 6 months after term...
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Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1953-05, Vol.83 (1), p.14-17 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | Summary
Twenty-four mice of the Marsh-Albino strain were injected daily for a period of 3 months with desoxycorticosterone acetate (0.2 mg/0.1 cc) in sesame oil. Of these, 1 was killed 3 months after termination of treatment but showed no evidence of tumor, while 9 others, killed 6 months after termination of treatments had subcutaneous tumors of two histological types, fibrosarcoma and myosarcoma. The remaining 10 mice are still alive; all show gross evidence of tumor formation, which became evident 6 months after completion of treatment. |
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ISSN: | 0037-9727 1535-3702 1535-3699 |
DOI: | 10.3181/00379727-83-20250 |