Effect of an Antagonist of Pteroylglutamic Acid on the Leukemia of Ak Mice.

Effect of an Antagonist of Pteroylglutamic Acid on the Leukemia of Ak Mice.

Summary The transplanted leukemia of Ak mice can be partially controlled either by a pteroylglutamic acid-free diet, combined with succinylsulfathiazole and a crude antagonist of pteroylglutamic acid, or by the addition of large amounts of the crude antagonist to an unpurified “normal mouse diet.” L...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1949-05, Vol.71 (1), p.107-112
Hauptverfasser: Weir, David R., Welch, Arnold D., Heinle, Robert W.
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 112
container_issue 1
container_start_page 107
container_title Experimental biology and medicine (Maywood, N.J.)
container_volume 71
creator Weir, David R.
Welch, Arnold D.
Heinle, Robert W.
description Summary The transplanted leukemia of Ak mice can be partially controlled either by a pteroylglutamic acid-free diet, combined with succinylsulfathiazole and a crude antagonist of pteroylglutamic acid, or by the addition of large amounts of the crude antagonist to an unpurified “normal mouse diet.” Life is prolonged and the severity of the disease is reduced.
doi_str_mv 10.3181/00379727-71-17099
format Article
fullrecord <record><control><sourceid>sage_cross</sourceid><recordid>TN_cdi_sage_journals_10_3181_00379727_71_17099</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.3181_00379727-71-17099</sage_id><sourcerecordid>10.3181_00379727-71-17099</sourcerecordid><originalsourceid>FETCH-LOGICAL-c199t-5f837c858c103df7a07d97c69880ce8a0bf8d24f1d7e1dd3a0e07f06d53569133</originalsourceid><addsrcrecordid>eNp9kE1PwzAMhiMEEmXwA7jlD2TYC62TYzUNmBiCA5yjkI_RfbSoaQ_797QbXDlZst_Hsh_GbhGmEhXeAUjSNCNBKJBA6zOWYS5zIQutz1k2zsUYuGRXKW0AMKdZkbHnRYzBdbyJ3Na8rDu7buoqHRtvXWibw2696zu7rxwvXeV5U_PuK_BV6LdhX9kxV275S-XC9JpdRLtL4ea3TtjHw-J9_iRWr4_LebkSDrXuRB6VJKdy5RCkj2SBvCZXaKXABWXhMyo_u4_oKaD30kIAilD44Z1Co5QThqe9rm1SakM03221t-3BIJjRhvmzYQjN0cbATE9MsutgNk3f1sOJ_wA_O2dejQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Effect of an Antagonist of Pteroylglutamic Acid on the Leukemia of Ak Mice.</title><source>Alma/SFX Local Collection</source><creator>Weir, David R. ; Welch, Arnold D. ; Heinle, Robert W.</creator><creatorcontrib>Weir, David R. ; Welch, Arnold D. ; Heinle, Robert W.</creatorcontrib><description>Summary The transplanted leukemia of Ak mice can be partially controlled either by a pteroylglutamic acid-free diet, combined with succinylsulfathiazole and a crude antagonist of pteroylglutamic acid, or by the addition of large amounts of the crude antagonist to an unpurified “normal mouse diet.” Life is prolonged and the severity of the disease is reduced.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-71-17099</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><ispartof>Experimental biology and medicine (Maywood, N.J.), 1949-05, Vol.71 (1), p.107-112</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c199t-5f837c858c103df7a07d97c69880ce8a0bf8d24f1d7e1dd3a0e07f06d53569133</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Weir, David R.</creatorcontrib><creatorcontrib>Welch, Arnold D.</creatorcontrib><creatorcontrib>Heinle, Robert W.</creatorcontrib><title>Effect of an Antagonist of Pteroylglutamic Acid on the Leukemia of Ak Mice.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><description>Summary The transplanted leukemia of Ak mice can be partially controlled either by a pteroylglutamic acid-free diet, combined with succinylsulfathiazole and a crude antagonist of pteroylglutamic acid, or by the addition of large amounts of the crude antagonist to an unpurified “normal mouse diet.” Life is prolonged and the severity of the disease is reduced.</description><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1949</creationdate><recordtype>article</recordtype><recordid>eNp9kE1PwzAMhiMEEmXwA7jlD2TYC62TYzUNmBiCA5yjkI_RfbSoaQ_797QbXDlZst_Hsh_GbhGmEhXeAUjSNCNBKJBA6zOWYS5zIQutz1k2zsUYuGRXKW0AMKdZkbHnRYzBdbyJ3Na8rDu7buoqHRtvXWibw2696zu7rxwvXeV5U_PuK_BV6LdhX9kxV275S-XC9JpdRLtL4ea3TtjHw-J9_iRWr4_LebkSDrXuRB6VJKdy5RCkj2SBvCZXaKXABWXhMyo_u4_oKaD30kIAilD44Z1Co5QThqe9rm1SakM03221t-3BIJjRhvmzYQjN0cbATE9MsutgNk3f1sOJ_wA_O2dejQ</recordid><startdate>194905</startdate><enddate>194905</enddate><creator>Weir, David R.</creator><creator>Welch, Arnold D.</creator><creator>Heinle, Robert W.</creator><general>SAGE Publications</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>194905</creationdate><title>Effect of an Antagonist of Pteroylglutamic Acid on the Leukemia of Ak Mice.</title><author>Weir, David R. ; Welch, Arnold D. ; Heinle, Robert W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c199t-5f837c858c103df7a07d97c69880ce8a0bf8d24f1d7e1dd3a0e07f06d53569133</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1949</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weir, David R.</creatorcontrib><creatorcontrib>Welch, Arnold D.</creatorcontrib><creatorcontrib>Heinle, Robert W.</creatorcontrib><collection>CrossRef</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Weir, David R.</au><au>Welch, Arnold D.</au><au>Heinle, Robert W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of an Antagonist of Pteroylglutamic Acid on the Leukemia of Ak Mice.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><date>1949-05</date><risdate>1949</risdate><volume>71</volume><issue>1</issue><spage>107</spage><epage>112</epage><pages>107-112</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary The transplanted leukemia of Ak mice can be partially controlled either by a pteroylglutamic acid-free diet, combined with succinylsulfathiazole and a crude antagonist of pteroylglutamic acid, or by the addition of large amounts of the crude antagonist to an unpurified “normal mouse diet.” Life is prolonged and the severity of the disease is reduced.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><doi>10.3181/00379727-71-17099</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0037-9727
ispartof Experimental biology and medicine (Maywood, N.J.), 1949-05, Vol.71 (1), p.107-112
issn 0037-9727
1535-3702
1535-3699
language eng
recordid cdi_sage_journals_10_3181_00379727_71_17099
source Alma/SFX Local Collection
title Effect of an Antagonist of Pteroylglutamic Acid on the Leukemia of Ak Mice.
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T03%3A04%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-sage_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20an%20Antagonist%20of%20Pteroylglutamic%20Acid%20on%20the%20Leukemia%20of%20Ak%20Mice.&rft.jtitle=Experimental%20biology%20and%20medicine%20(Maywood,%20N.J.)&rft.au=Weir,%20David%20R.&rft.date=1949-05&rft.volume=71&rft.issue=1&rft.spage=107&rft.epage=112&rft.pages=107-112&rft.issn=0037-9727&rft.eissn=1535-3699&rft_id=info:doi/10.3181/00379727-71-17099&rft_dat=%3Csage_cross%3E10.3181_00379727-71-17099%3C/sage_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_sage_id=10.3181_00379727-71-17099&rfr_iscdi=true