Effect of an Antagonist of Pteroylglutamic Acid on the Leukemia of Ak Mice.

Summary The transplanted leukemia of Ak mice can be partially controlled either by a pteroylglutamic acid-free diet, combined with succinylsulfathiazole and a crude antagonist of pteroylglutamic acid, or by the addition of large amounts of the crude antagonist to an unpurified “normal mouse diet.” L...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1949-05, Vol.71 (1), p.107-112
Hauptverfasser: Weir, David R., Welch, Arnold D., Heinle, Robert W.
Format: Artikel
Sprache:eng
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Zusammenfassung:Summary The transplanted leukemia of Ak mice can be partially controlled either by a pteroylglutamic acid-free diet, combined with succinylsulfathiazole and a crude antagonist of pteroylglutamic acid, or by the addition of large amounts of the crude antagonist to an unpurified “normal mouse diet.” Life is prolonged and the severity of the disease is reduced.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-71-17099