Billroth I, Gastric Resection: Extent Necessary to Protect Against Histamine-Provoked Ulcer.

Conclusion Small gastric resections (25 and 50%) in dogs, when accompanied by no afferent loop (Billroth I), are accompanied by a high incidence of histamine invoked stomal ulcer. When a three-quarter gastric resection (75%) is done, however, stomal ulcer cannot be produced with histamine. These experiments suggest that it is unlikely that substitution of the Billroth I for the Billroth II plan of operation, in which a short afferent duodenal loop is employed, will protect against recurrent ulcer with less sacrifice of stomach. A three-quarter resection will protect against the histamine-in-beeswax provoked ulcer, whether the operation is carried out on the Billroth I or II plan of operation.