Chemotherapeutic Properties of Streptomycin

Summary Streptomycin seems to possess some advantages over streptothricin particularly from the point of view of toxicity and its greater action against certain gram-negative and gram-positive bacteria in vivo. Although certain batches of streptomycin appear to have the same order of toxicity as streptothricin, the findings suggest that under proper conditions a relatively non-toxic preparation can be obtained. Streptothricin seems to be much more effective in vitro against pathogenic fungi than streptomycin.