Experimental Diabetes Produced by Alloxan
Summary The administration of alloxan in one suitable dose produces a pancreatic experimental diabetes. Satisfactory animals exhibit a prolonged high blood-sugar level that is maintained for weeks. KO renal lesions are observed in such animals and the fat and glycogen content of the liver is within...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1944-03, Vol.55 (3), p.214-216 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Summary
The administration of alloxan in one suitable dose produces a pancreatic experimental diabetes. Satisfactory animals exhibit a prolonged high blood-sugar level that is maintained for weeks. KO renal lesions are observed in such animals and the fat and glycogen content of the liver is within normal limits. Adrenal and pancreatic islet cellular changes may explain the character of the acute phase. |
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| ISSN: | 0037-9727 1535-3702 1535-3699 |
| DOI: | 10.3181/00379727-55-14524 |