Lack of Endotoxin in Borrelia hispanica and Treponema pallidum 1
Abstract Borrelia hispanica from infected guinea pigs and Treponema pallidum from testicular syphilomas of rabbits were assayed for the presence of endotoxin with the Limulus lysate test. A suspension of Borrelia, containing 1.3 × 108 spirochetes/ml, was nonreactive both when it was tested as intact...
Gespeichert in:
Veröffentlicht in: | Proceedings of the Society for Experimental Biology and Medicine 1983-10, Vol.174 (1), p.47-52 |
---|---|
Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 52 |
---|---|
container_issue | 1 |
container_start_page | 47 |
container_title | Proceedings of the Society for Experimental Biology and Medicine |
container_volume | 174 |
creator | Hardy, Paul H. Levin, Jack |
description | Abstract
Borrelia hispanica from infected guinea pigs and Treponema pallidum from testicular syphilomas of rabbits were assayed for the presence of endotoxin with the Limulus lysate test. A suspension of Borrelia, containing 1.3 × 108 spirochetes/ml, was nonreactive both when it was tested as intact organisms, and when tested after disruption of the spirochetes by sonication. Eight different suspensions of treponemes, ranging from 0.6 × 109 to 3 × 109 treponemes/ml, were negative at a 1:10 dilution and were no more active than control suspensions of normal rabbit testes. Therefore, it was concluded that T. pallidum, as well as the Borrelia, possessed no endotoxin. |
doi_str_mv | 10.3181/00379727-174-41702 |
format | Article |
fullrecord | <record><control><sourceid>sage</sourceid><recordid>TN_cdi_sage_journals_10_3181_00379727_174_41702</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.3181_00379727-174-41702</sage_id><sourcerecordid>10.3181_00379727-174-41702</sourcerecordid><originalsourceid>FETCH-sage_journals_10_3181_00379727_174_417023</originalsourceid><addsrcrecordid>eNqVjk0KwjAUhIMoWH8u4CoXiL7XtMbuRFFcuHQfHjbV1JqURsHj24oeQBgYGL6Bj7EZwlziChcAUmUqVgJVIhJUEPdYhKlMhVxmWZ9FHSA6YshGIZQAsIQYIrY-0vnGfcF3LvcP_7KOt9n4pjGVJX61oSZnz8TJ5fzUmNo7cydeU1XZ_HnnOGGDgqpgpt8es8V-d9oeRKCL0aV_Nq6dNYLuRPVPVLei-iMq_3-8AdmyQus</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Lack of Endotoxin in Borrelia hispanica and Treponema pallidum 1</title><source>Alma/SFX Local Collection</source><creator>Hardy, Paul H. ; Levin, Jack</creator><creatorcontrib>Hardy, Paul H. ; Levin, Jack</creatorcontrib><description>Abstract
Borrelia hispanica from infected guinea pigs and Treponema pallidum from testicular syphilomas of rabbits were assayed for the presence of endotoxin with the Limulus lysate test. A suspension of Borrelia, containing 1.3 × 108 spirochetes/ml, was nonreactive both when it was tested as intact organisms, and when tested after disruption of the spirochetes by sonication. Eight different suspensions of treponemes, ranging from 0.6 × 109 to 3 × 109 treponemes/ml, were negative at a 1:10 dilution and were no more active than control suspensions of normal rabbit testes. Therefore, it was concluded that T. pallidum, as well as the Borrelia, possessed no endotoxin.</description><identifier>ISSN: 0037-9727</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-174-41702</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><ispartof>Proceedings of the Society for Experimental Biology and Medicine, 1983-10, Vol.174 (1), p.47-52</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Hardy, Paul H.</creatorcontrib><creatorcontrib>Levin, Jack</creatorcontrib><title>Lack of Endotoxin in Borrelia hispanica and Treponema pallidum 1</title><title>Proceedings of the Society for Experimental Biology and Medicine</title><description>Abstract
Borrelia hispanica from infected guinea pigs and Treponema pallidum from testicular syphilomas of rabbits were assayed for the presence of endotoxin with the Limulus lysate test. A suspension of Borrelia, containing 1.3 × 108 spirochetes/ml, was nonreactive both when it was tested as intact organisms, and when tested after disruption of the spirochetes by sonication. Eight different suspensions of treponemes, ranging from 0.6 × 109 to 3 × 109 treponemes/ml, were negative at a 1:10 dilution and were no more active than control suspensions of normal rabbit testes. Therefore, it was concluded that T. pallidum, as well as the Borrelia, possessed no endotoxin.</description><issn>0037-9727</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqVjk0KwjAUhIMoWH8u4CoXiL7XtMbuRFFcuHQfHjbV1JqURsHj24oeQBgYGL6Bj7EZwlziChcAUmUqVgJVIhJUEPdYhKlMhVxmWZ9FHSA6YshGIZQAsIQYIrY-0vnGfcF3LvcP_7KOt9n4pjGVJX61oSZnz8TJ5fzUmNo7cydeU1XZ_HnnOGGDgqpgpt8es8V-d9oeRKCL0aV_Nq6dNYLuRPVPVLei-iMq_3-8AdmyQus</recordid><startdate>198310</startdate><enddate>198310</enddate><creator>Hardy, Paul H.</creator><creator>Levin, Jack</creator><general>SAGE Publications</general><scope/></search><sort><creationdate>198310</creationdate><title>Lack of Endotoxin in Borrelia hispanica and Treponema pallidum 1</title><author>Hardy, Paul H. ; Levin, Jack</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-sage_journals_10_3181_00379727_174_417023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hardy, Paul H.</creatorcontrib><creatorcontrib>Levin, Jack</creatorcontrib><jtitle>Proceedings of the Society for Experimental Biology and Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hardy, Paul H.</au><au>Levin, Jack</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lack of Endotoxin in Borrelia hispanica and Treponema pallidum 1</atitle><jtitle>Proceedings of the Society for Experimental Biology and Medicine</jtitle><date>1983-10</date><risdate>1983</risdate><volume>174</volume><issue>1</issue><spage>47</spage><epage>52</epage><pages>47-52</pages><issn>0037-9727</issn><eissn>1535-3699</eissn><abstract>Abstract
Borrelia hispanica from infected guinea pigs and Treponema pallidum from testicular syphilomas of rabbits were assayed for the presence of endotoxin with the Limulus lysate test. A suspension of Borrelia, containing 1.3 × 108 spirochetes/ml, was nonreactive both when it was tested as intact organisms, and when tested after disruption of the spirochetes by sonication. Eight different suspensions of treponemes, ranging from 0.6 × 109 to 3 × 109 treponemes/ml, were negative at a 1:10 dilution and were no more active than control suspensions of normal rabbit testes. Therefore, it was concluded that T. pallidum, as well as the Borrelia, possessed no endotoxin.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><doi>10.3181/00379727-174-41702</doi></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0037-9727 |
ispartof | Proceedings of the Society for Experimental Biology and Medicine, 1983-10, Vol.174 (1), p.47-52 |
issn | 0037-9727 1535-3699 |
language | eng |
recordid | cdi_sage_journals_10_3181_00379727_174_41702 |
source | Alma/SFX Local Collection |
title | Lack of Endotoxin in Borrelia hispanica and Treponema pallidum 1 |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T13%3A19%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-sage&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lack%20of%20Endotoxin%20in%20Borrelia%20hispanica%20and%20Treponema%20pallidum%201&rft.jtitle=Proceedings%20of%20the%20Society%20for%20Experimental%20Biology%20and%20Medicine&rft.au=Hardy,%20Paul%20H.&rft.date=1983-10&rft.volume=174&rft.issue=1&rft.spage=47&rft.epage=52&rft.pages=47-52&rft.issn=0037-9727&rft.eissn=1535-3699&rft_id=info:doi/10.3181/00379727-174-41702&rft_dat=%3Csage%3E10.3181_00379727-174-41702%3C/sage%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_sage_id=10.3181_00379727-174-41702&rfr_iscdi=true |