Inhibition of Marrow Growth by Cyclic AMP 1

Summary Cyclic AMP, dibutyryl cyclic AMP, epinephrine, and theophylline inhibited growth of marrow colonies in vitro. The interpretation of this observation is uncertain since various adenine nucleotides had a similar effect and since several substances lowering intracellular cyclic AMP levels were...

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Veröffentlicht in:Proceedings of the Society for Experimental Biology and Medicine 1971-10, Vol.138 (1), p.57-59
Hauptverfasser: Morley, Alec, Quesenberry, Peter, Garrity, Marianne, Stohlman, Frederick
Format: Artikel
Sprache:eng
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Zusammenfassung:Summary Cyclic AMP, dibutyryl cyclic AMP, epinephrine, and theophylline inhibited growth of marrow colonies in vitro. The interpretation of this observation is uncertain since various adenine nucleotides had a similar effect and since several substances lowering intracellular cyclic AMP levels were unable to reverse the inhibitory effect of exogenous cyclic AMP.
ISSN:0037-9727
1535-3699
DOI:10.3181/00379727-138-35831