Biochemical Events During Interferon Synthesis in L Cells Infected with Newcastle Disease Virus 1

Biochemical Events During Interferon Synthesis in L Cells Infected with Newcastle Disease Virus 1

Summary The time of interferon induction in L cells has been shown to occur from 8 to 12 hr after infection with NDV. Although interferon synthesis represents the production of a new cellular protein, the rates of protein and nuclear RNA synthesis were found to actually undergo a rapid decrease foll...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the Society for Experimental Biology and Medicine 1971-04, Vol.136 (4), p.1078-1081
Hauptverfasser: Lancz, Gerald J., Johnson, Terry C.
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1081
container_issue 4
container_start_page 1078
container_title Proceedings of the Society for Experimental Biology and Medicine
container_volume 136
creator Lancz, Gerald J.
Johnson, Terry C.
description Summary The time of interferon induction in L cells has been shown to occur from 8 to 12 hr after infection with NDV. Although interferon synthesis represents the production of a new cellular protein, the rates of protein and nuclear RNA synthesis were found to actually undergo a rapid decrease following NDV infection. A comparison of the temperal relationship between alterations in overall macromolecular synthesis and interferon production indicated that the synthesis of L cell interferon occurred when macromolecular biosynthesis was considerably depressed.
doi_str_mv 10.3181/00379727-136-35431
format Article
fullrecord <record><control><sourceid>sage</sourceid><recordid>TN_cdi_sage_journals_10_3181_00379727_136_35431</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.3181_00379727-136-35431</sage_id><sourcerecordid>10.3181_00379727-136-35431</sourcerecordid><originalsourceid>FETCH-sage_journals_10_3181_00379727_136_354313</originalsourceid><addsrcrecordid>eNqVj0FOwzAQRS0EEqHtBVjNBUzHdZOQLW0RlSo2VN1aVpg0rowjeZxWvT0JggOw-tL_7y-eEI8Kn7R6VnNEXVblopRKF1LnS61uRKZynUtdVNWtyEZAjsS9eGA-IWKBC8yEfXFd3dKXq62HzZlCYlj30YUjbEOi2FDsAnxcQ2qJHYMLsIMVec_D3lCd6BMuLrXwTpfacvIEa8dkmeDgYs-gpuKusZ5p9psTMX_d7Fdvku2RzKnrYxhqo9CMJubPxAwm5sdE___xDeBsTxw</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Biochemical Events During Interferon Synthesis in L Cells Infected with Newcastle Disease Virus 1</title><source>Alma/SFX Local Collection</source><creator>Lancz, Gerald J. ; Johnson, Terry C.</creator><creatorcontrib>Lancz, Gerald J. ; Johnson, Terry C.</creatorcontrib><description>Summary The time of interferon induction in L cells has been shown to occur from 8 to 12 hr after infection with NDV. Although interferon synthesis represents the production of a new cellular protein, the rates of protein and nuclear RNA synthesis were found to actually undergo a rapid decrease following NDV infection. A comparison of the temperal relationship between alterations in overall macromolecular synthesis and interferon production indicated that the synthesis of L cell interferon occurred when macromolecular biosynthesis was considerably depressed.</description><identifier>ISSN: 0037-9727</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-136-35431</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><ispartof>Proceedings of the Society for Experimental Biology and Medicine, 1971-04, Vol.136 (4), p.1078-1081</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Lancz, Gerald J.</creatorcontrib><creatorcontrib>Johnson, Terry C.</creatorcontrib><title>Biochemical Events During Interferon Synthesis in L Cells Infected with Newcastle Disease Virus 1</title><title>Proceedings of the Society for Experimental Biology and Medicine</title><description>Summary The time of interferon induction in L cells has been shown to occur from 8 to 12 hr after infection with NDV. Although interferon synthesis represents the production of a new cellular protein, the rates of protein and nuclear RNA synthesis were found to actually undergo a rapid decrease following NDV infection. A comparison of the temperal relationship between alterations in overall macromolecular synthesis and interferon production indicated that the synthesis of L cell interferon occurred when macromolecular biosynthesis was considerably depressed.</description><issn>0037-9727</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqVj0FOwzAQRS0EEqHtBVjNBUzHdZOQLW0RlSo2VN1aVpg0rowjeZxWvT0JggOw-tL_7y-eEI8Kn7R6VnNEXVblopRKF1LnS61uRKZynUtdVNWtyEZAjsS9eGA-IWKBC8yEfXFd3dKXq62HzZlCYlj30YUjbEOi2FDsAnxcQ2qJHYMLsIMVec_D3lCd6BMuLrXwTpfacvIEa8dkmeDgYs-gpuKusZ5p9psTMX_d7Fdvku2RzKnrYxhqo9CMJubPxAwm5sdE___xDeBsTxw</recordid><startdate>197104</startdate><enddate>197104</enddate><creator>Lancz, Gerald J.</creator><creator>Johnson, Terry C.</creator><general>SAGE Publications</general><scope/></search><sort><creationdate>197104</creationdate><title>Biochemical Events During Interferon Synthesis in L Cells Infected with Newcastle Disease Virus 1</title><author>Lancz, Gerald J. ; Johnson, Terry C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-sage_journals_10_3181_00379727_136_354313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lancz, Gerald J.</creatorcontrib><creatorcontrib>Johnson, Terry C.</creatorcontrib><jtitle>Proceedings of the Society for Experimental Biology and Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lancz, Gerald J.</au><au>Johnson, Terry C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biochemical Events During Interferon Synthesis in L Cells Infected with Newcastle Disease Virus 1</atitle><jtitle>Proceedings of the Society for Experimental Biology and Medicine</jtitle><date>1971-04</date><risdate>1971</risdate><volume>136</volume><issue>4</issue><spage>1078</spage><epage>1081</epage><pages>1078-1081</pages><issn>0037-9727</issn><eissn>1535-3699</eissn><abstract>Summary The time of interferon induction in L cells has been shown to occur from 8 to 12 hr after infection with NDV. Although interferon synthesis represents the production of a new cellular protein, the rates of protein and nuclear RNA synthesis were found to actually undergo a rapid decrease following NDV infection. A comparison of the temperal relationship between alterations in overall macromolecular synthesis and interferon production indicated that the synthesis of L cell interferon occurred when macromolecular biosynthesis was considerably depressed.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><doi>10.3181/00379727-136-35431</doi></addata></record>
fulltext fulltext
identifier ISSN: 0037-9727
ispartof Proceedings of the Society for Experimental Biology and Medicine, 1971-04, Vol.136 (4), p.1078-1081
issn 0037-9727
1535-3699
language eng
recordid cdi_sage_journals_10_3181_00379727_136_35431
source Alma/SFX Local Collection
title Biochemical Events During Interferon Synthesis in L Cells Infected with Newcastle Disease Virus 1
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T08%3A39%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-sage&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Biochemical%20Events%20During%20Interferon%20Synthesis%20in%20L%20Cells%20Infected%20with%20Newcastle%20Disease%20Virus%201&rft.jtitle=Proceedings%20of%20the%20Society%20for%20Experimental%20Biology%20and%20Medicine&rft.au=Lancz,%20Gerald%20J.&rft.date=1971-04&rft.volume=136&rft.issue=4&rft.spage=1078&rft.epage=1081&rft.pages=1078-1081&rft.issn=0037-9727&rft.eissn=1535-3699&rft_id=info:doi/10.3181/00379727-136-35431&rft_dat=%3Csage%3E10.3181_00379727-136-35431%3C/sage%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_sage_id=10.3181_00379727-136-35431&rfr_iscdi=true