Effect of Thyroid States on Uterine Sensitivity to Estrogen 1

Summary The effect of hyper- and hypothyroidism on uterine wet weight, total protein, and SDH activity was studied in estrogen (2.0 μg of estradiol 17β/kg of body wt for 3 days)- and nonestrogen-treated ovariectomized rats. Uterine SDH activity appeared to increase in hyperthyroidism independent of...

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Veröffentlicht in:Proceedings of the Society for Experimental Biology and Medicine 1970-09, Vol.134 (4), p.947-951
Hauptverfasser: Ruh, M. F., Ruh, T. S., Klitgaard, H. M.
Format: Artikel
Sprache:eng
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Zusammenfassung:Summary The effect of hyper- and hypothyroidism on uterine wet weight, total protein, and SDH activity was studied in estrogen (2.0 μg of estradiol 17β/kg of body wt for 3 days)- and nonestrogen-treated ovariectomized rats. Uterine SDH activity appeared to increase in hyperthyroidism independent of the effect of estrogens. Uterine wet weight and total protein were significantly increased with estrogen treatment in the hypo- and euthyroid groups but not the hyper thyroid group. Uterine wet weights and total protein were not significantly different in uteri from control, thyroparathyroidectomized, or thyroxine-treated ovariectomized rats given a total dose of 0.5 μg of estradiol 17β.
ISSN:0037-9727
1535-3699
DOI:10.3181/00379727-134-34918