GC-MS analysis, phytochemical composition of L. essential oil with pharmacological assessments: antioxidant, antibacterial, and antifungal activities
The genus Hertia , which belongs to the Asteraceae family, is a flowering genus with 12 species found in Africa, North and South. Among the species present in Algeria, Hertia cheirifolia L. is distributed in the eastern regions of Algeria. The aim of this study is to evaluate its phytochemical compo...
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Veröffentlicht in: | RSC advances 2024-07, Vol.14 (31), p.22548-22559 |
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Zusammenfassung: | The genus
Hertia
, which belongs to the Asteraceae family, is a flowering genus with 12 species found in Africa, North and South. Among the species present in Algeria,
Hertia cheirifolia
L. is distributed in the eastern regions of Algeria. The aim of this study is to evaluate its phytochemical composition with following pharmacological assessments: the antioxidant, antibacterial, and antifungal activities of
Hertia cheirifolia
L. essential oil (EO). GC-MS analysis was used to analyze the chemical constituents of
H. cheirifolia
essential oil. The antioxidant capacity was assessed using DPPH, FRAP, and H
2
O
2
tests. The EO was also tested for its ability to inhibit six strains of microorganisms, including two Gram (+) and four Gram (−) strains. The antifungal activity was tested by analyzing the effect of the EO on the mycelial growth of
Fusarium oxysporum
f.sp.
lycopersici
(FOL) fungi. Results showed that primary volatile components were α-pinene (32.59%), 2-(1-cyclopent-1-enyl-1-methylethyl) cyclopentanone (14.62%), (−)-germacrene D (11.37%), and bakkenolide A (9.57%).
H. cheirifolia
EO showed inhibitory effects against DPPH, H
2
O
2
, and FRAP (IC
50
= 0.34 ± 0.1, 0.053 ± 0.1, and 0.047 ± 0.01 mg mL
−1
, respectively). The EO also exhibited moderate antibacterial effects against
Staphylococcus aureus
ATCC 25923 (
S. aureus
),
Streptococcus pneumoniae
ATCC 49619 (
S. pneumoniae
), and
Enterobacter aerogenes
ATCC 13048 (
E. aerogenes
), as well as significant antioxidant potential and varied antifungal activity based on dosage and fungal strain. To our knowledge, no previous research has examined the antifungal capacity of
H. cheirifolia
oil and oil-mycelial development of the FOL relationship. To fully explore the benefits of
H. cheirifolia
EO, more
in vivo
research is necessary, along with more testing on other bacterial and fungal strains.
The genus
Hertia
, which belongs to the Asteraceae family, is a flowering genus with 12 species found in Africa, North and South. |
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ISSN: | 2046-2069 |
DOI: | 10.1039/d4ra03578j |