Synthesis of -β-brominated alkenyl isothiocyanates dehydrogenation of alkyl isothiocyanates

This study presents a new dehydrogenative synthesis of alkenyl isothiocyanates, providing compounds with bromo and isothiocyanate groups. These reactive functionalities offer versatility for further transformations. Application in an amine sensor utilizing a coumarin-attached product demonstrates practical utility. This streamlined approach facilitates access to alkenyl isothiocyanates, valuable tools for biological studies. A new dehydrogenative synthesis of alkenyl isothiocyanates has been developed; the reaction provides compounds with bromo and isothiocyanate groups. The products are applicable to various further transformations.