Detection and discrimination of glutathione among biological thiols based on oxalyl dihydrazide decorated sulfur nanodots

Detection and discrimination of glutathione among biological thiols based on oxalyl dihydrazide decorated sulfur nanodots

The quantitative detection and discrimination of glutathione (GSH) were achieved based on oxalyl dihydrazide (ODH) decorated sulfur nanodots. ODH resulted in the aggregation and fluorescence quenching of the sulfur nanodots, and GSH selectively triggered fluorescence recovery through forming stronge...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2024-03, Vol.6 (2), p.276-2763
Hauptverfasser: Xing, Yifei, Zhu, Sha, Li, Jiayue, Li, Wei, Wang, Zhenguang, Shi, Yu-e
Format: Artikel
Sprache:eng
Schlagworte:
Bonding strength
Fluorescence
Glutathione
Hydrogen bonds
Sulfur
Thiols
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Zusammenfassung:The quantitative detection and discrimination of glutathione (GSH) were achieved based on oxalyl dihydrazide (ODH) decorated sulfur nanodots. ODH resulted in the aggregation and fluorescence quenching of the sulfur nanodots, and GSH selectively triggered fluorescence recovery through forming stronger hydrogen bonds with ODH than other biological thiols. The quantitative detection and discrimination of glutathione (GSH) were achieved based on oxalyl dihydrazide (ODH) decorated sulfur nanodots.
ISSN:1359-7345
1364-548X
DOI:10.1039/d4cc00135d