Concise syntheses of (−)-habiterpenol and (+)-2,3--habiterpenol redox radical cyclization of alkenylsilane

The concise syntheses of (−)-habiterpenol and (+)-2,3- epi -habiterpenol from (3a R )-(+)-sclareolide and 6-methoxyindanone in 11 and 12 steps, respectively, were enabled by the regioselective addition of the TMS-indenyl anion and the facile stereoselective metal hydride hydrogen atom transfer (MHAT)-initiated redox radical cyclization of alkenylsilane. The concise synthesis of (−)-habiterpenol in 11 steps was enabled by MHAT-initiated redox radical cyclization of alkenylsilane.