One-pot synthesis of 11-sulfenyl dibenzodiazepines tandem sulfenylation/cyclization of -isocyanodiaryl amines and diaryl disulfides

A one-pot sulfenylation/cyclization of o -isocyanodiaryl amines has been described for the preparation of 11-sulfenyl dibenzodiazepines. This AgI-catalyzed reaction covers an unexplored tandem process to give seven-membered N-heterocycles. This transformation shows a broad range of substrate scope, simple operation, and moderate to good yields under aerobic conditions. Diphenyl diselenide can also be produced in an acceptable yield. AgI-catalyzed one-pot sulfenylation/cyclization of o -isocyanodiaryl amines has been described for the preparation of 11-sulfenyl dibenzodiazepines in moderate to good yields.