Efficient end-group functionalization and diblock copolymer synthesis Au() polymer reagents

Herein, we describe the synthesis of bench-stable organometallic Au( iii ) terminated polymer reagents. These reagents mediate the chemoselective S -arylation of thiol-containing small molecules and polymers to yield functionalized mono-telechelic polymers and diblock copolymers, respectively. These transformations proceed rapidly within minutes and produce conjugates in quantitative conversion, making this strategy a robust addition to the polymer functionalization toolbox. Au( iii ) polymer reagents provide facile access to semi-telechelic and diblock copolymers.