Triple -defluoroetherification of (trifluoromethyl)alkenes with fluoroalkylated alcohols: access to fluoroalkylated orthoesters C(sp)-F bond cleavage
The triple ipso -defluoroetherification of (trifluoromethyl)alkenes with fluoroalkylated alcohols by C(sp 3 )-F bond cleavage is reported, delivering various fluoroalkylated orthoesters in high yields. This reaction is transition-metal free and gram-scalable, features mild reaction conditions, and t...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2023-06, Vol.59 (53), p.8238-8241 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
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| Zusammenfassung: | The triple
ipso
-defluoroetherification of (trifluoromethyl)alkenes with fluoroalkylated alcohols by C(sp
3
)-F bond cleavage is reported, delivering various fluoroalkylated orthoesters in high yields. This reaction is transition-metal free and gram-scalable, features mild reaction conditions, and tolerates diverse functional groups.
Triple
ipso
-defluoroetherification of (trifluoromethyl)alkenes with fluoroalkylated alcohols to synthesize fluoroalkylated orthoesters by C(sp
3
)-F bond cleavage. |
|---|---|
| ISSN: | 1359-7345 1364-548X |
| DOI: | 10.1039/d3cc01760e |