Palladium-catalysed deaminative/decarboxylative cross-coupling of organoammonium salts with carboxylic acids

A palladium-catalysed carbon-carbon bond-forming reaction via deaminative/decarboxylative cross-coupling of organoammonium salts with carboxylic acids was developed. Under the reaction conditions, polyfluoroaromatic carboxylic acids, propiolic acids and α-cyano benzyl carboxylic acid reacted smoothl...

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Veröffentlicht in:Organic & biomolecular chemistry 2023-02, Vol.21 (7), p.1384-1388
Hauptverfasser: Liu, Kuan, Ding, Dexiang, Xing, Weitao, Liu, Long, Zhang, Shuo, Meng, Qi, Chen, Tieqiao
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container_end_page 1388
container_issue 7
container_start_page 1384
container_title Organic & biomolecular chemistry
container_volume 21
creator Liu, Kuan
Ding, Dexiang
Xing, Weitao
Liu, Long
Zhang, Shuo
Meng, Qi
Chen, Tieqiao
description A palladium-catalysed carbon-carbon bond-forming reaction via deaminative/decarboxylative cross-coupling of organoammonium salts with carboxylic acids was developed. Under the reaction conditions, polyfluoroaromatic carboxylic acids, propiolic acids and α-cyano benzyl carboxylic acid reacted smoothly with benzyl ammonium salts to produce the corresponding carbon-carbon coupling products in good-to-excellent yields. A palladium-catalysed C-C bond-forming reaction via deaminative and decarboxylative cross-coupling of organoammonium salts with a series of carboxylic acids (including polyfluoroaromatic, propiolic and α-cyano benzyl carboxylic acids) was developed.
doi_str_mv 10.1039/d2ob02251f
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Under the reaction conditions, polyfluoroaromatic carboxylic acids, propiolic acids and α-cyano benzyl carboxylic acid reacted smoothly with benzyl ammonium salts to produce the corresponding carbon-carbon coupling products in good-to-excellent yields. A palladium-catalysed C-C bond-forming reaction via deaminative and decarboxylative cross-coupling of organoammonium salts with a series of carboxylic acids (including polyfluoroaromatic, propiolic and α-cyano benzyl carboxylic acids) was developed.</description><identifier>ISSN: 1477-0520</identifier><identifier>EISSN: 1477-0539</identifier><identifier>DOI: 10.1039/d2ob02251f</identifier><identifier>PMID: 36652381</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Ammonium ; Ammonium salts ; Carbon ; Carboxylic acids ; Cross coupling ; Palladium ; Salts</subject><ispartof>Organic &amp; biomolecular chemistry, 2023-02, Vol.21 (7), p.1384-1388</ispartof><rights>Copyright Royal Society of Chemistry 2023</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c267t-a7aa977f8ac7964910e99bada8da52a64b767b5ac90f9f2b606206ac468ccc793</citedby><cites>FETCH-LOGICAL-c267t-a7aa977f8ac7964910e99bada8da52a64b767b5ac90f9f2b606206ac468ccc793</cites><orcidid>0000-0002-6472-5057 ; 0000-0002-9787-9538</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36652381$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Kuan</creatorcontrib><creatorcontrib>Ding, Dexiang</creatorcontrib><creatorcontrib>Xing, Weitao</creatorcontrib><creatorcontrib>Liu, Long</creatorcontrib><creatorcontrib>Zhang, Shuo</creatorcontrib><creatorcontrib>Meng, Qi</creatorcontrib><creatorcontrib>Chen, Tieqiao</creatorcontrib><title>Palladium-catalysed deaminative/decarboxylative cross-coupling of organoammonium salts with carboxylic acids</title><title>Organic &amp; biomolecular chemistry</title><addtitle>Org Biomol Chem</addtitle><description>A palladium-catalysed carbon-carbon bond-forming reaction via deaminative/decarboxylative cross-coupling of organoammonium salts with carboxylic acids was developed. 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source Royal Society Of Chemistry Journals; Alma/SFX Local Collection
subjects Ammonium
Ammonium salts
Carbon
Carboxylic acids
Cross coupling
Palladium
Salts
title Palladium-catalysed deaminative/decarboxylative cross-coupling of organoammonium salts with carboxylic acids
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