Thioamide directed iridium()-catalyzed CH arylation of ferrocenes with aryl boronic acids

The first Ir( i )-catalyzed thioamide-assisted C-H arylation of ferrocenes with aryl boronic acids under base-free mild reaction conditions in the presence of Ag 2 CO 3 as an oxidant with eco-friendly 2-MeTHF as a solvent was developed. This reaction has a wide range of substrates (37 examples) and functional group tolerance (1894% yields), and provides promising access to aryl thioamide-ferrocene compounds with good yields and regioselectivity. The Ir( i )-catalyzed thioamide-assisted CH arylation of ferrocenes with aryl boronic acids under base-free mild reaction conditions was developed, which has a wide range of substrates and functional group tolerance with good yields and regioselectivity.