Tosyl/pyrrolyl-capped 1,3-enynes -BuOK-assisted reaction of TosMIC with acylethynylpyrroles: a new feature of this popular reagent

1-Tosyl-4-pyrrolyl-1,3-enynes have been synthesized in 37-68% yields by t -BuOK-assisted chemo selective reaction (reflux in THF, 1 h) of 2-(acylethynyl)pyrroles with tosylmethylisocyanide (TosMIC), a widespread reagent, which here manifests a new functionality. 1-Tosyl-4-pyrrolyl-1,3-enynes have be...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	New journal of chemistry 2022-09, Vol.46 (35), p.16646-1665
Hauptverfasser:	Gotsko, Maxim D, Saliy, Ivan V, Sobenina, Lyubov' N, Ushakov, Igor A, Trofimov, Boris A
Format:	Artikel
Sprache:
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	1-Tosyl-4-pyrrolyl-1,3-enynes have been synthesized in 37-68% yields by t -BuOK-assisted chemo selective reaction (reflux in THF, 1 h) of 2-(acylethynyl)pyrroles with tosylmethylisocyanide (TosMIC), a widespread reagent, which here manifests a new functionality. 1-Tosyl-4-pyrrolyl-1,3-enynes have been synthesized in 37-68% yields by t -BuOK-assisted chemo selective reaction (reflux in THF, 1 h) of 2-(acylethynyl)pyrroles with tosylmethylisocyanide (TosMIC), a widespread reagent, which here manifests a new functionality.
ISSN:	1144-0546 1369-9261
DOI:	10.1039/d2nj02827a