Taming photocatalysis in flow: easy and speedy preparation of α-aminoamide derivatives

α-Aminoamides are reiterative molecular subunits in transcendental molecules, which bear attractive functionalities for (bio)synthetic purposes. Herein, their preparation by harnessing flow photocatalysis is described, which provides significant improvements over other catalytic methods in terms of efficiency while outperforming an analogous batch setup. A reaction time of five minutes, operational simplicity and absence of purification steps for the isolation of final products evidence an enhanced performance. The benefits of using photoflow technology for the synthesis of α-aminoamides with elevated complexity compared to classic batch technology are described. Higher yields, no purification steps, and the opportunity of easy scalability are featured.