A switchable DNA origami/plasmonic hybrid device with a precisely tuneable DNA-free interparticle gap

We here show a reconfigurable DNA/plasmonic nanodevice with a precisely tunable and DNA-free interparticle gap. The nanodevice comprises two DNA boxes for the size-selective incorporation of nanoparticles in a face-to-face orientation and an underlying switchable DNA platform for the controlled and reversible adjustment of the interparticle distance. A switchable nanophotonic hybrid device consisting of DNA origami and gold nanospheres with a tuneable and molecule-free dimer hot spot for plasmon-assisted molecular spectroscopy is presented.