DNA-mediated hierarchical organization of gold nanoprisms into 3D aggregates and their application in surface-enhanced Raman scattering

Colloidal crystallization using DNA provides a robust method for fabricating highly programmable nanoparticle superstructures with collective plasmonic properties. Here, we report on the DNA-guided fabrication of 3D plasmonic aggregates from polydisperse gold nanoprisms. We first construct 1D crystals via DNA-induced and shape-directed face-to-face assembly of anisotropic gold nanoprisms. Using the near- T m thermal annealing approach that promotes long-range DNA-induced interaction and ordering, we then assemble 1D nanoprism crystals into a 3D nanoprism aggregate that exhibits a polycrystalline morphology with nanoscale ordering and microscale dimensions. The presence of closely packed nanoprism arrays over a large area gives rise to strong near-field plasmonic coupling and generates a high density of plasmonic hot spots within the 3D nanoprism aggregates that exhibit excellent surface-enhanced Raman scattering performance. The plasmonic 3D nanoprism aggregates demonstrate significant SERS enhancement (