A metal-organic cage-based nanoagent for enhanced photodynamic antitumor therapy
Herein, we report, for the first time, a Pd 6 L 8 (NO 3 ) 5.4 (ICG) 6.6 (ICG = indocyanine green) cage-based hexagonal nanoplate ( 3 ) via a combined nanoprecipitation and solid-state anion-exchange approach. Nanoplate 3 possesses enhanced near-infrared (NIR) light-triggered 1 O 2 generation, high c...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2021-08, Vol.57 (64), p.7954-7957 |
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| container_issue | 64 |
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| container_title | Chemical communications (Cambridge, England) |
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| creator | Li, Wen-Yan Zhao, Chao-Wei Zhang, Yue-Feng Guan, Qun Wan, Jing-Jing Ma, Jian-Ping Li, Yan-An Dong, Yu-Bin |
| description | Herein, we report, for the first time, a Pd
6
L
8
(NO
3
)
5.4
(ICG)
6.6
(ICG = indocyanine green) cage-based hexagonal nanoplate (
3
)
via
a combined nanoprecipitation and solid-state anion-exchange approach. Nanoplate
3
possesses enhanced near-infrared (NIR) light-triggered
1
O
2
generation, high cellular uptake selective lysosome-targeting ability, and, consequently, excellent antineoplastic activity.
A Pd
6
L
8
(NO
3
)
5.4
(ICG)
6.6
-based nanoagent (ICG = indocyanine green) displays a highly efficient antitumor activity due to its enhanced NIR light-triggered
1
O
2
generation, high cellular uptake, and selective lysosome-targeting ability. |
| doi_str_mv | 10.1039/d1cc02629a |
| format | Article |
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6
L
8
(NO
3
)
5.4
(ICG)
6.6
(ICG = indocyanine green) cage-based hexagonal nanoplate (
3
)
via
a combined nanoprecipitation and solid-state anion-exchange approach. Nanoplate
3
possesses enhanced near-infrared (NIR) light-triggered
1
O
2
generation, high cellular uptake selective lysosome-targeting ability, and, consequently, excellent antineoplastic activity.
A Pd
6
L
8
(NO
3
)
5.4
(ICG)
6.6
-based nanoagent (ICG = indocyanine green) displays a highly efficient antitumor activity due to its enhanced NIR light-triggered
1
O
2
generation, high cellular uptake, and selective lysosome-targeting ability.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/d1cc02629a</identifier><language>eng</language><publisher>Cambridge: Royal Society of Chemistry</publisher><subject>Anion exchanging ; Cages ; Crystallography ; Infrared radiation</subject><ispartof>Chemical communications (Cambridge, England), 2021-08, Vol.57 (64), p.7954-7957</ispartof><rights>Copyright Royal Society of Chemistry 2021</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c314t-d96da6a688aa8f185bbf80c07877f3f568bcf6ecedc23ceb76a172c8a5021f7b3</citedby><cites>FETCH-LOGICAL-c314t-d96da6a688aa8f185bbf80c07877f3f568bcf6ecedc23ceb76a172c8a5021f7b3</cites><orcidid>0000-0002-5522-5106 ; 0000-0002-5300-3307 ; 0000-0002-7083-4022 ; 0000-0002-9698-8863</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Li, Wen-Yan</creatorcontrib><creatorcontrib>Zhao, Chao-Wei</creatorcontrib><creatorcontrib>Zhang, Yue-Feng</creatorcontrib><creatorcontrib>Guan, Qun</creatorcontrib><creatorcontrib>Wan, Jing-Jing</creatorcontrib><creatorcontrib>Ma, Jian-Ping</creatorcontrib><creatorcontrib>Li, Yan-An</creatorcontrib><creatorcontrib>Dong, Yu-Bin</creatorcontrib><title>A metal-organic cage-based nanoagent for enhanced photodynamic antitumor therapy</title><title>Chemical communications (Cambridge, England)</title><description>Herein, we report, for the first time, a Pd
6
L
8
(NO
3
)
5.4
(ICG)
6.6
(ICG = indocyanine green) cage-based hexagonal nanoplate (
3
)
via
a combined nanoprecipitation and solid-state anion-exchange approach. Nanoplate
3
possesses enhanced near-infrared (NIR) light-triggered
1
O
2
generation, high cellular uptake selective lysosome-targeting ability, and, consequently, excellent antineoplastic activity.
A Pd
6
L
8
(NO
3
)
5.4
(ICG)
6.6
-based nanoagent (ICG = indocyanine green) displays a highly efficient antitumor activity due to its enhanced NIR light-triggered
1
O
2
generation, high cellular uptake, and selective lysosome-targeting ability.</description><subject>Anion exchanging</subject><subject>Cages</subject><subject>Crystallography</subject><subject>Infrared radiation</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNpd0M9LwzAUB_AgCs7pxbtQ8CJCNWmaND2O-hMGelDwVl7TZOtok5qkh_33Zk4UzOXlx4f3whehc4JvCKblbUukxBnPSjhAM0J5nrJcfBzu9qxMC5qzY3Ti_QbHRZiYoddFMqgAfWrdCkwnEwkrlTbgVZsYMDaeTEi0dYkyazAyXo9rG2y7NTBEDiZ0YRrie1grB-P2FB1p6L06-6lz9P5w_1Y9pcuXx-dqsUwlJXlI25K3wIELASA0EaxptMASF6IoNNWMi0ZqruI8mVGpmoIDKTIpgOGM6KKhc3S17zs6-zkpH-qh81L1PRhlJ19njFGREVHkkV7-oxs7ORN_t1Mlx4ITGtX1XklnvXdK16PrBnDbmuB6F259R6rqO9xFxBd77Lz8dX_h0y_bEnbJ</recordid><startdate>20210810</startdate><enddate>20210810</enddate><creator>Li, Wen-Yan</creator><creator>Zhao, Chao-Wei</creator><creator>Zhang, Yue-Feng</creator><creator>Guan, Qun</creator><creator>Wan, Jing-Jing</creator><creator>Ma, Jian-Ping</creator><creator>Li, Yan-An</creator><creator>Dong, Yu-Bin</creator><general>Royal Society of Chemistry</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5522-5106</orcidid><orcidid>https://orcid.org/0000-0002-5300-3307</orcidid><orcidid>https://orcid.org/0000-0002-7083-4022</orcidid><orcidid>https://orcid.org/0000-0002-9698-8863</orcidid></search><sort><creationdate>20210810</creationdate><title>A metal-organic cage-based nanoagent for enhanced photodynamic antitumor therapy</title><author>Li, Wen-Yan ; Zhao, Chao-Wei ; Zhang, Yue-Feng ; Guan, Qun ; Wan, Jing-Jing ; Ma, Jian-Ping ; Li, Yan-An ; Dong, Yu-Bin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c314t-d96da6a688aa8f185bbf80c07877f3f568bcf6ecedc23ceb76a172c8a5021f7b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Anion exchanging</topic><topic>Cages</topic><topic>Crystallography</topic><topic>Infrared radiation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Wen-Yan</creatorcontrib><creatorcontrib>Zhao, Chao-Wei</creatorcontrib><creatorcontrib>Zhang, Yue-Feng</creatorcontrib><creatorcontrib>Guan, Qun</creatorcontrib><creatorcontrib>Wan, Jing-Jing</creatorcontrib><creatorcontrib>Ma, Jian-Ping</creatorcontrib><creatorcontrib>Li, Yan-An</creatorcontrib><creatorcontrib>Dong, Yu-Bin</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Wen-Yan</au><au>Zhao, Chao-Wei</au><au>Zhang, Yue-Feng</au><au>Guan, Qun</au><au>Wan, Jing-Jing</au><au>Ma, Jian-Ping</au><au>Li, Yan-An</au><au>Dong, Yu-Bin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A metal-organic cage-based nanoagent for enhanced photodynamic antitumor therapy</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><date>2021-08-10</date><risdate>2021</risdate><volume>57</volume><issue>64</issue><spage>7954</spage><epage>7957</epage><pages>7954-7957</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>Herein, we report, for the first time, a Pd
6
L
8
(NO
3
)
5.4
(ICG)
6.6
(ICG = indocyanine green) cage-based hexagonal nanoplate (
3
)
via
a combined nanoprecipitation and solid-state anion-exchange approach. Nanoplate
3
possesses enhanced near-infrared (NIR) light-triggered
1
O
2
generation, high cellular uptake selective lysosome-targeting ability, and, consequently, excellent antineoplastic activity.
A Pd
6
L
8
(NO
3
)
5.4
(ICG)
6.6
-based nanoagent (ICG = indocyanine green) displays a highly efficient antitumor activity due to its enhanced NIR light-triggered
1
O
2
generation, high cellular uptake, and selective lysosome-targeting ability.</abstract><cop>Cambridge</cop><pub>Royal Society of Chemistry</pub><doi>10.1039/d1cc02629a</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-5522-5106</orcidid><orcidid>https://orcid.org/0000-0002-5300-3307</orcidid><orcidid>https://orcid.org/0000-0002-7083-4022</orcidid><orcidid>https://orcid.org/0000-0002-9698-8863</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2021-08, Vol.57 (64), p.7954-7957 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_rsc_primary_d1cc02629a |
| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Anion exchanging Cages Crystallography Infrared radiation |
| title | A metal-organic cage-based nanoagent for enhanced photodynamic antitumor therapy |
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