Novel albumin-binding photothermal agent for targeted fluorescent imaging and photothermal therapy of cancer

In this work, we present a novel photothermal agent ICG-IBA-RGD based on albumin-binding strategy for enhanced tumor targeting imaging and photothermal therapy. In vitro and in vivo experiments demonstrated that ICG-IBA-RGD exhibits excellent photothermal conversion capability and high tumor ablatio...

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Veröffentlicht in:RSC advances 2021-02, Vol.11 (13), p.7226-723
Hauptverfasser: Yu, Cheng, Xiao, Enhua, Xu, Pengfei, Lin, Jingjing, Hu, Linan, Zhang, Jie, Dai, Shengzhen, Ding, Zhuyuan, Xiao, Yuyang, Chen, Zhu
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Zusammenfassung:In this work, we present a novel photothermal agent ICG-IBA-RGD based on albumin-binding strategy for enhanced tumor targeting imaging and photothermal therapy. In vitro and in vivo experiments demonstrated that ICG-IBA-RGD exhibits excellent photothermal conversion capability and high tumor ablation efficiency. In this work, we present a novel photothermal agent ICG-IBA-RGD based on albumin-binding strategy for enhanced tumor targeting imaging and photothermal therapy.
ISSN:2046-2069
DOI:10.1039/d0ra09653a