Rhodium-catalyzed -acrylation of aryl ketone -methyl oximes with cyclopropenones

An efficient Rh-catalyzed ortho -acrylation reaction for the synthesis of chalcones from O -methyl ketoximes and cyclopropenones via C-H bond activation has been described. This cross-coupling reaction exhibits high functional group tolerance and regioselectivity. A wide range of chalcone derivatives are obtained in moderate to good yields under mild conditions. We have developed a rhodium-catalyzed ortho -C-H acrylation of O -methyl ketoximes with cyclopropenones leading to the formation of chalcone derivatives.