Magnetic resonance thermometry using a Gd-based contrast agent

Magnetic resonance thermometry using a Gd-based contrast agent

The complexes described here serve as contrast agents for magnetic resonance imaging thermometry. The complexes differentially enhance contrast between 275 and 325 K. The basis of the temperature response of the fluorinated contrast complex is the modulation of water exchange caused by trifluorometh...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2021-02, Vol.57 (14), p.177-1773
Hauptverfasser: Subasinghe, S. A. Amali S, Romero, Jonathan, Ward, Cassandra L, Bailey, Matthew D, Zehner, Donna R, Mehta, Prakrut J, Carniato, Fabio, Botta, Mauro, Yustein, Jason T, Pautler, Robia G, Allen, Matthew J
Format: Artikel
Sprache:eng
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Zusammenfassung:The complexes described here serve as contrast agents for magnetic resonance imaging thermometry. The complexes differentially enhance contrast between 275 and 325 K. The basis of the temperature response of the fluorinated contrast complex is the modulation of water exchange caused by trifluoromethyl groups that can be chemically controlled. The complexes described here serve as contrast agents for magnetic resonance imaging thermometry.
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc06400a