Dual functional luminescent nanoprobes for monitoring oxygen and chloride concentration changes in cells

Dual functional luminescent nanoprobes for monitoring oxygen and chloride concentration changes in cells

A dual functional nanoprobe Pd-Q + @PDMS was proposed to simultaneously monitor Cl − and O 2 , leading to the determination of an average Cl − concentration of 85.7 ± 5.5 mM in lysosomes of HeLa cells. Mimicking ischemic conditions, the cells exhibited a luminescence change corresponding to a decrea...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2020-12, Vol.56 (95), p.1498-14983
Hauptverfasser: Li, Jing, Zhai, Jingying, Wang, Yifu, Yang, Wei, Xie, Xiaojiang
Format: Artikel
Sprache:eng
Schlagworte:
Lysosomes
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Zusammenfassung:A dual functional nanoprobe Pd-Q + @PDMS was proposed to simultaneously monitor Cl − and O 2 , leading to the determination of an average Cl − concentration of 85.7 ± 5.5 mM in lysosomes of HeLa cells. Mimicking ischemic conditions, the cells exhibited a luminescence change corresponding to a decreasing subcellular Cl − concentration. The first dual functional luminescent nanoprobe to monitor cellular Cl − and O 2 .
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc06258h