Mitochondria-targeting NO gas nanogenerator for augmenting mild photothermal therapy in the NIR-II biowindow

An intelligent nitric oxide gas-releasing nanoplatform based on CuS-nanoplates has been designed to overcome the heat endurance of tumor cells by the inhibition of HSP90 expression with the released NO gas in mitochondria and thereby realize enhanced PTT under mild temperature conditions. A mitochon...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2020-11, Vol.56 (92), p.14491-14494
Hauptverfasser: Wu, Canchen, Wang, Danqi, Cen, Moupan, Cao, Leyu, Ding, Yue, Wang, Jin, Yuan, Xiaolei, Wang, Yang, Chen, Tingting, Yao, Yong
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 14494
container_issue 92
container_start_page 14491
container_title Chemical communications (Cambridge, England)
container_volume 56
creator Wu, Canchen
Wang, Danqi
Cen, Moupan
Cao, Leyu
Ding, Yue
Wang, Jin
Yuan, Xiaolei
Wang, Yang
Chen, Tingting
Yao, Yong
description An intelligent nitric oxide gas-releasing nanoplatform based on CuS-nanoplates has been designed to overcome the heat endurance of tumor cells by the inhibition of HSP90 expression with the released NO gas in mitochondria and thereby realize enhanced PTT under mild temperature conditions. A mitochondria-targeting NO gas-releasing nanoplatform based on CuS-nanoplates has been designed for augmenting photothermal therapy by the synergistic effect.
doi_str_mv 10.1039/d0cc05125j
format Article
fullrecord <record><control><sourceid>proquest_rsc_p</sourceid><recordid>TN_cdi_rsc_primary_d0cc05125j</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2457970976</sourcerecordid><originalsourceid>FETCH-LOGICAL-c355t-33301363a2463bf73d3ab08a9c6c2948bb1dd2b2f7cc9c95ded042e69124fb513</originalsourceid><addsrcrecordid>eNpd0d1LwzAQAPAiCs7pi-9CwBcRqvlo2uZR5ldlbiAKvpU0SbuMNqlJy9h_b7uJggfH3cOP47gLgnMEbxAk7FZCISBFmK4PggkicRTSKP08HHvKwoRE9Dg48X4Nh0A0nQT1q-6sWFkjneZhx12lOm0qsFiCintguLGVMsrxzjpQDsn7qlFmZxpdS9CubGe7lXINr8FYebsF2owtWGRvYZaBQtuNNtJuToOjktdenf3UafDx-PA-ew7ny6dsdjcPBaG0CwkhcNidcBzFpCgTIgkvYMqZiAVmUVoUSEpc4DIRgglGpZIwwipmCEdlQRGZBlf7ua2zX73yXd5oL1Rdc6Ns73Mc0YQlkCXxQC__0bXtnRm2G1SMU5YQTAZ1vVfCWe-dKvPW6Ya7bY5gPh4-v4ez2e7wLwO-2GPnxa_7ewz5BtHsgAI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2462897323</pqid></control><display><type>article</type><title>Mitochondria-targeting NO gas nanogenerator for augmenting mild photothermal therapy in the NIR-II biowindow</title><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Wu, Canchen ; Wang, Danqi ; Cen, Moupan ; Cao, Leyu ; Ding, Yue ; Wang, Jin ; Yuan, Xiaolei ; Wang, Yang ; Chen, Tingting ; Yao, Yong</creator><creatorcontrib>Wu, Canchen ; Wang, Danqi ; Cen, Moupan ; Cao, Leyu ; Ding, Yue ; Wang, Jin ; Yuan, Xiaolei ; Wang, Yang ; Chen, Tingting ; Yao, Yong</creatorcontrib><description>An intelligent nitric oxide gas-releasing nanoplatform based on CuS-nanoplates has been designed to overcome the heat endurance of tumor cells by the inhibition of HSP90 expression with the released NO gas in mitochondria and thereby realize enhanced PTT under mild temperature conditions. A mitochondria-targeting NO gas-releasing nanoplatform based on CuS-nanoplates has been designed for augmenting photothermal therapy by the synergistic effect.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/d0cc05125j</identifier><language>eng</language><publisher>Cambridge: Royal Society of Chemistry</publisher><subject>Copper sulfides ; Mitochondria ; Nanogenerators ; Nitric oxide</subject><ispartof>Chemical communications (Cambridge, England), 2020-11, Vol.56 (92), p.14491-14494</ispartof><rights>Copyright Royal Society of Chemistry 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c355t-33301363a2463bf73d3ab08a9c6c2948bb1dd2b2f7cc9c95ded042e69124fb513</citedby><cites>FETCH-LOGICAL-c355t-33301363a2463bf73d3ab08a9c6c2948bb1dd2b2f7cc9c95ded042e69124fb513</cites><orcidid>0000-0001-5566-4822 ; 0000-0003-2500-5708 ; 0000-0002-8660-7246</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Wu, Canchen</creatorcontrib><creatorcontrib>Wang, Danqi</creatorcontrib><creatorcontrib>Cen, Moupan</creatorcontrib><creatorcontrib>Cao, Leyu</creatorcontrib><creatorcontrib>Ding, Yue</creatorcontrib><creatorcontrib>Wang, Jin</creatorcontrib><creatorcontrib>Yuan, Xiaolei</creatorcontrib><creatorcontrib>Wang, Yang</creatorcontrib><creatorcontrib>Chen, Tingting</creatorcontrib><creatorcontrib>Yao, Yong</creatorcontrib><title>Mitochondria-targeting NO gas nanogenerator for augmenting mild photothermal therapy in the NIR-II biowindow</title><title>Chemical communications (Cambridge, England)</title><description>An intelligent nitric oxide gas-releasing nanoplatform based on CuS-nanoplates has been designed to overcome the heat endurance of tumor cells by the inhibition of HSP90 expression with the released NO gas in mitochondria and thereby realize enhanced PTT under mild temperature conditions. A mitochondria-targeting NO gas-releasing nanoplatform based on CuS-nanoplates has been designed for augmenting photothermal therapy by the synergistic effect.</description><subject>Copper sulfides</subject><subject>Mitochondria</subject><subject>Nanogenerators</subject><subject>Nitric oxide</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNpd0d1LwzAQAPAiCs7pi-9CwBcRqvlo2uZR5ldlbiAKvpU0SbuMNqlJy9h_b7uJggfH3cOP47gLgnMEbxAk7FZCISBFmK4PggkicRTSKP08HHvKwoRE9Dg48X4Nh0A0nQT1q-6sWFkjneZhx12lOm0qsFiCintguLGVMsrxzjpQDsn7qlFmZxpdS9CubGe7lXINr8FYebsF2owtWGRvYZaBQtuNNtJuToOjktdenf3UafDx-PA-ew7ny6dsdjcPBaG0CwkhcNidcBzFpCgTIgkvYMqZiAVmUVoUSEpc4DIRgglGpZIwwipmCEdlQRGZBlf7ua2zX73yXd5oL1Rdc6Ns73Mc0YQlkCXxQC__0bXtnRm2G1SMU5YQTAZ1vVfCWe-dKvPW6Ya7bY5gPh4-v4ez2e7wLwO-2GPnxa_7ewz5BtHsgAI</recordid><startdate>20201119</startdate><enddate>20201119</enddate><creator>Wu, Canchen</creator><creator>Wang, Danqi</creator><creator>Cen, Moupan</creator><creator>Cao, Leyu</creator><creator>Ding, Yue</creator><creator>Wang, Jin</creator><creator>Yuan, Xiaolei</creator><creator>Wang, Yang</creator><creator>Chen, Tingting</creator><creator>Yao, Yong</creator><general>Royal Society of Chemistry</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-5566-4822</orcidid><orcidid>https://orcid.org/0000-0003-2500-5708</orcidid><orcidid>https://orcid.org/0000-0002-8660-7246</orcidid></search><sort><creationdate>20201119</creationdate><title>Mitochondria-targeting NO gas nanogenerator for augmenting mild photothermal therapy in the NIR-II biowindow</title><author>Wu, Canchen ; Wang, Danqi ; Cen, Moupan ; Cao, Leyu ; Ding, Yue ; Wang, Jin ; Yuan, Xiaolei ; Wang, Yang ; Chen, Tingting ; Yao, Yong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c355t-33301363a2463bf73d3ab08a9c6c2948bb1dd2b2f7cc9c95ded042e69124fb513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Copper sulfides</topic><topic>Mitochondria</topic><topic>Nanogenerators</topic><topic>Nitric oxide</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wu, Canchen</creatorcontrib><creatorcontrib>Wang, Danqi</creatorcontrib><creatorcontrib>Cen, Moupan</creatorcontrib><creatorcontrib>Cao, Leyu</creatorcontrib><creatorcontrib>Ding, Yue</creatorcontrib><creatorcontrib>Wang, Jin</creatorcontrib><creatorcontrib>Yuan, Xiaolei</creatorcontrib><creatorcontrib>Wang, Yang</creatorcontrib><creatorcontrib>Chen, Tingting</creatorcontrib><creatorcontrib>Yao, Yong</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wu, Canchen</au><au>Wang, Danqi</au><au>Cen, Moupan</au><au>Cao, Leyu</au><au>Ding, Yue</au><au>Wang, Jin</au><au>Yuan, Xiaolei</au><au>Wang, Yang</au><au>Chen, Tingting</au><au>Yao, Yong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mitochondria-targeting NO gas nanogenerator for augmenting mild photothermal therapy in the NIR-II biowindow</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><date>2020-11-19</date><risdate>2020</risdate><volume>56</volume><issue>92</issue><spage>14491</spage><epage>14494</epage><pages>14491-14494</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>An intelligent nitric oxide gas-releasing nanoplatform based on CuS-nanoplates has been designed to overcome the heat endurance of tumor cells by the inhibition of HSP90 expression with the released NO gas in mitochondria and thereby realize enhanced PTT under mild temperature conditions. A mitochondria-targeting NO gas-releasing nanoplatform based on CuS-nanoplates has been designed for augmenting photothermal therapy by the synergistic effect.</abstract><cop>Cambridge</cop><pub>Royal Society of Chemistry</pub><doi>10.1039/d0cc05125j</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0001-5566-4822</orcidid><orcidid>https://orcid.org/0000-0003-2500-5708</orcidid><orcidid>https://orcid.org/0000-0002-8660-7246</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 1359-7345
ispartof Chemical communications (Cambridge, England), 2020-11, Vol.56 (92), p.14491-14494
issn 1359-7345
1364-548X
language eng
recordid cdi_rsc_primary_d0cc05125j
source Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Copper sulfides
Mitochondria
Nanogenerators
Nitric oxide
title Mitochondria-targeting NO gas nanogenerator for augmenting mild photothermal therapy in the NIR-II biowindow
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T01%3A06%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_rsc_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Mitochondria-targeting%20NO%20gas%20nanogenerator%20for%20augmenting%20mild%20photothermal%20therapy%20in%20the%20NIR-II%20biowindow&rft.jtitle=Chemical%20communications%20(Cambridge,%20England)&rft.au=Wu,%20Canchen&rft.date=2020-11-19&rft.volume=56&rft.issue=92&rft.spage=14491&rft.epage=14494&rft.pages=14491-14494&rft.issn=1359-7345&rft.eissn=1364-548X&rft_id=info:doi/10.1039/d0cc05125j&rft_dat=%3Cproquest_rsc_p%3E2457970976%3C/proquest_rsc_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2462897323&rft_id=info:pmid/&rfr_iscdi=true