Mitochondria-targeting NO gas nanogenerator for augmenting mild photothermal therapy in the NIR-II biowindow
An intelligent nitric oxide gas-releasing nanoplatform based on CuS-nanoplates has been designed to overcome the heat endurance of tumor cells by the inhibition of HSP90 expression with the released NO gas in mitochondria and thereby realize enhanced PTT under mild temperature conditions. A mitochon...
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2020-11, Vol.56 (92), p.14491-14494 |
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container_issue | 92 |
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container_title | Chemical communications (Cambridge, England) |
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creator | Wu, Canchen Wang, Danqi Cen, Moupan Cao, Leyu Ding, Yue Wang, Jin Yuan, Xiaolei Wang, Yang Chen, Tingting Yao, Yong |
description | An intelligent nitric oxide gas-releasing nanoplatform based on CuS-nanoplates has been designed to overcome the heat endurance of tumor cells by the inhibition of HSP90 expression with the released NO gas in mitochondria and thereby realize enhanced PTT under mild temperature conditions.
A mitochondria-targeting NO gas-releasing nanoplatform based on CuS-nanoplates has been designed for augmenting photothermal therapy by the synergistic effect. |
doi_str_mv | 10.1039/d0cc05125j |
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source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
subjects | Copper sulfides Mitochondria Nanogenerators Nitric oxide |
title | Mitochondria-targeting NO gas nanogenerator for augmenting mild photothermal therapy in the NIR-II biowindow |
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