The Ag-promoted -CH arylation of alcohols

We herein report the functionalization of -CH in alcohols through cross-dehydrogenative coupling reactions. Selectfluor was used as a mild oxidant. In situ -generated HF participated in the reaction and no external strong acid was necessary. A variety of heteroaryl-substituted alcohols were achieved with good yields and with good functional group tolerance. We herein report the functionalization of -CH in alcohols through cross-dehydrogenative coupling reactions.