The role of apolipoprotein- and vitronectin-enriched protein corona on lipid nanoparticles for targeted delivery and transfection of oligonucleotides in murine tumor models

The application of lipid-based nanoparticle (LNP) delivery systems remains a popular strategy for the systemic delivery of gene therapies to specific disease targets, including solid tumors. It is now well acknowledged that upon systemic administration, biomolecules from blood will adsorb onto nanop...

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Veröffentlicht in:	Nanoscale 2019-10, Vol.11 (4), p.1886-18824
Hauptverfasser:	Chen, Dongyu, Parayath, Neha, Ganesh, Shanthi, Wang, Weimin, Amiji, Mansoor
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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