Effects of honey from Mimosa quadrivalvis L. (malícia) produced by the Melipona subnitida D. (jandaíra) stingless bee on dyslipidaemic ratsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8fo01044g

This study assessed the effects of supplementation with honey from Mimosa quadrivalvis L. (malícia) (MH) produced by jandaíra stingless bees ( Melipona subnitida D.) on the lipid metabolism, antioxidant status and some intestinal health parameters of rats with diet-induced dyslipidaemia. Rats were r...

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Hauptverfasser: Bezerra, Maria Luiza Rolim, de Souza, Evandro Leite, de Sousa, Janaína Maria Batista, Lima, Marcos dos Santos, Alves, Adriano Francisco, Almeida, Maria das Graças, Coutinho Alves, Raquel, Veríssimo de Araújo, Emmanuel, Soares, Naís Lira, da Silva, Gabriel Araújo, Magnani, Marciane, Aquino, Jailane de Souza
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Sprache:eng
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Zusammenfassung:This study assessed the effects of supplementation with honey from Mimosa quadrivalvis L. (malícia) (MH) produced by jandaíra stingless bees ( Melipona subnitida D.) on the lipid metabolism, antioxidant status and some intestinal health parameters of rats with diet-induced dyslipidaemia. Rats were randomly divided into four groups: healthy control (HC), dyslipidaemic control (DC), healthy experimental (EHH) and dyslipidaemic experimental (EDH). Malícia honey (MH) was administered (1000 mL kg −1 ) via orogastric feeding for 35 days. Dyslipidaemic rats supplemented with MH showed lower food consumption, increased glucose tolerance and superoxide dismutase (SOD) activity, and decreased total cholesterol, LDL and AST blood levels. Counts of Bifidobacterium spp. and Lactobacillus spp. and excretion of organic acids in faeces increased in dyslipidaemic rats supplemented with MH. MH supplementation protected the colon and liver from tissue damage induced by the dyslipidaemic diet. These results show the beneficial effects of MH on the lipid metabolism, antioxidant status and intestinal health of rats with diet-induced dyslipidaemia. The supplementation with malícia honey alters the lipid metabolism, antioxidant status and intestinal health parameters of rats with diet-induced dyslipidaemia.
ISSN:2042-6496
2042-650X
DOI:10.1039/c8fo01044g