Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies: in vivo imaging of diesel exhaust particulates in miceElectronic supplementary information (ESI) available. See DOI: 10.1039/c8cc08304e

As a robust radioanalytical method for tracking carbonaceous particulates in vivo , polycyclic aromatic hydrocarbons from diesel exhaust were labeled with a radioactive-iodine-tagged pyrene analogue. Single-photon emission computed tomography and biodistribution studies showed high uptake and slow clearance of this matter in the respiratory system, which may underlie its severe toxicity. As a robust radioanalytical method for tracking carbonaceous particulates in vivo , polycyclic aromatic hydrocarbons from diesel exhaust were labeled with a radioactive-iodine-tagged pyrene analogue.